Intermediates

3,4-Difluorobenzoic Acid

  • CAS No.455-86-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 3,4-Difluorobenzoic Acid for advanced organic synthesis. Reliable supply with COA.

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Product Technical Details

Product Overview

3,4-Difluorobenzoic Acid is a critically important fluorinated aromatic building block utilized extensively in the field of advanced organic synthesis. Characterized by the presence of two fluorine atoms at the meta and para positions of the benzene ring, this compound offers unique electronic properties that enhance the metabolic stability and lipophilicity of downstream molecules. Our manufacturing facility produces this chemical intermediate using state-of-the-art fluorination technologies, ensuring consistent quality and high yield for industrial-scale applications.

As a key precursor in the development of novel pharmaceutical agents and agrochemical formulations, 3,4-Difluorobenzoic Acid serves as a versatile substrate for various coupling reactions. The strategic placement of fluorine substituents allows chemists to fine-tune the biological activity of final products without significantly altering steric parameters. We are committed to supplying this material with exceptional purity levels to support rigorous research and development pipelines.

Key Specifications

Quality control is paramount in our production process. Each batch undergoes stringent analytical testing to verify compliance with international standards. The physical and chemical properties listed below represent our typical factory specifications, ensuring reliability for your synthesis routes.

ParameterSpecification
Chemical Name3,4-Difluorobenzoic Acid
CAS Number455-86-7
Molecular FormulaC7H4F2O2
Molecular Weight158.10 g/mol
AppearanceWhite to Off-white Crystalline Powder
Purity (HPLC)≥ 99.0%
Melting Point120-122°C
Water Content≤ 0.5%

Industrial Applications

This fluorinated benzoic acid derivative finds widespread utility across multiple high-value sectors. In the pharmaceutical industry, it is frequently employed as a core structure for synthesizing kinase inhibitors and receptor modulators. The electron-withdrawing nature of the fluorine atoms facilitates specific nucleophilic aromatic substitutions, making it an ideal candidate for constructing complex heterocyclic systems.

Furthermore, the agrochemical sector utilizes this intermediate in the creation of next-generation herbicides and fungicides. The enhanced environmental stability provided by the fluorine substituents ensures prolonged efficacy in field applications. Additionally, materials science researchers leverage this compound in the development of liquid crystals and high-performance polymers, where thermal stability and dielectric properties are essential. Our team provides technical support to help optimize the integration of this material into your specific manufacturing process.

Quality Assurance and Packaging

We maintain a robust quality assurance system that tracks every stage of production from raw material sourcing to final dispatch. Comprehensive Certificates of Analysis (COA) are provided with every shipment, detailing batch-specific test results including purity, moisture content, and residual solvents. Our packaging solutions are designed to preserve product integrity during global transit.

Standard packaging consists of 25 kg fiber drums with inner polyethylene liners, ensuring protection against moisture and contamination. Customized packaging options are available upon request to accommodate specific logistical requirements. We recommend storing the product in a cool, ventilated area away from direct sunlight and incompatible substances. With our global distribution network, we ensure timely delivery to support your continuous production schedules.