Intermediates

3,4-Difluorobenzonitrile

  • CAS No.64248-62-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3,4-Difluorobenzonitrile (CAS 64248-62-0) designed for pharmaceutical and agrochemical synthesis. Reliable supply with strict quality control.

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Product Technical Details

Product Overview

3,4-Difluorobenzonitrile is a highly valued fluorinated organic intermediate widely utilized in modern chemical synthesis. Characterized by its stable aromatic structure and reactive nitrile group, this compound serves as a critical building block for developing advanced pharmaceutical agents, agrochemical solutions, and specialized liquid crystal materials. Our manufacturing process ensures exceptional consistency and purity, meeting the rigorous demands of global research and industrial production facilities.

The introduction of fluorine atoms at the 3 and 4 positions of the benzene ring significantly enhances the metabolic stability and lipophilicity of downstream molecules. This makes 3,4-Difluorobenzonitrile an essential precursor in the design of kinase inhibitors and other therapeutic compounds. Furthermore, its chemical properties facilitate various nucleophilic substitution reactions, allowing chemists to construct complex molecular architectures with high precision.

Technical Specifications

We adhere to strict quality management systems to guarantee that every batch meets or exceeds industry standards. The following table outlines the key physical and chemical parameters for our standard grade product.

Parameter Specification
Chemical Name 3,4-Difluorobenzonitrile
CAS Number 64248-62-0
Molecular Formula C7H3F2N
Molecular Weight 139.10 g/mol
Appearance White to light yellow crystalline powder
Assay (Purity) ≥99.0%
Moisture Content ≤0.2%
Melting Point 52-54°C
Boiling Point 180°C
Density 1.26 g/cm³

Industrial Applications

This fluorinated nitrile derivative finds extensive application across multiple high-tech sectors. In the pharmaceutical industry, it is employed as a key intermediate for synthesizing novel drug candidates targeting various diseases. The electron-withdrawing nature of the fluorine substituents allows for fine-tuning of biological activity and pharmacokinetic profiles in final drug products.

In agrochemical development, 3,4-Difluorobenzonitrile is used to create potent herbicides and pesticides that offer improved environmental stability and efficacy. Additionally, the material science sector utilizes this compound in the production of liquid crystal monomers, which are vital for high-performance display technologies. Its thermal stability and optical properties make it suitable for demanding electronic applications.

Quality Assurance and Handling

Our commitment to quality extends beyond mere specification compliance. Each production lot undergoes comprehensive analysis using advanced chromatography and spectroscopy techniques. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and transparency for our partners.

For optimal storage, the product should be kept in a cool, ventilated area away from direct sunlight and moisture. Standard packaging includes 25 kg drums, though we offer flexible customization to suit specific logistical requirements. Our team provides dedicated technical support to assist with synthesis route optimization and safe handling procedures, ensuring a seamless integration into your manufacturing process.