3,4-Difluorotoluene
- CAS No.2927-34-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3,4-Difluorotoluene (CAS 2927-34-6) is a versatile fluorinated aromatic intermediate widely used in the synthesis of pharmaceuticals and agrochemicals.
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Product Overview
3,4-Difluorotoluene is a high-value fluorinated aromatic compound serving as a critical building block in modern organic synthesis. With its unique substitution pattern—two adjacent fluorine atoms and a methyl group on the benzene ring—it offers exceptional reactivity and selectivity for constructing complex molecular architectures. This intermediate is extensively employed in the development of active pharmaceutical ingredients (APIs) and crop protection agents, where fluorine incorporation enhances metabolic stability, bioavailability, and binding affinity.
Specifications
| Molecular Formula | C7H6F2 |
|---|---|
| Molecular Weight | 128.12 g/mol |
| Density | 1.12 g/mL at 25 °C |
| Boiling Point | 110–113 °C |
| Flash Point | 77 °F (25 °C) |
| Refractive Index | n20/D 1.45 |
| Vapor Pressure | 26.7 mmHg at 25 °C |
| Appearance | Colorless to light yellow transparent liquid |
| Purity | ≥98% |
| Water Content | ≤0.5% |
Industrial Applications
As a specialty fluoroaromatic intermediate, 3,4-Difluorotoluene plays a pivotal role in multiple high-tech sectors:
- Pharmaceutical Synthesis: Serves as a key precursor in the manufacture of advanced therapeutic agents targeting neurological, oncological, and anti-infective pathways.
- Agrochemical Development: Used to construct novel herbicides, fungicides, and insecticides with improved environmental profiles and efficacy.
- Advanced Materials: Contributes to the production of liquid crystals, electronic chemicals, and specialty polymers requiring precise fluorination.
For safe handling, this material is classified under UN1993 as a flammable liquid (Hazard Class 3, Packing Group III). It should be stored in a cool, dry, well-ventilated area with containers tightly sealed to prevent moisture ingress and vapor release. Standard packaging includes 25 kg plastic drums or plastic-coated iron drums suitable for international transport.
