Intermediates

3-(4-Nitrophenyl)pyridine

  • CAS No.4282-46-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-(4-Nitrophenyl)pyridine (CAS 4282-46-6) designed for pharmaceutical synthesis, specifically as a key intermediate for Niraparib production.

Request Bulk Pricing

Product Technical Details

Product Overview

3-(4-Nitrophenyl)pyridine is a specialized organic compound widely recognized within the pharmaceutical industry as a critical building block for advanced therapeutic synthesis. As a nitro-substituted pyridine derivative, this chemical intermediate plays a pivotal role in the construction of complex molecular architectures required for modern medicine. Our facility produces this compound under strict quality control standards to ensure consistency and reliability for downstream manufacturing processes. We understand that the integrity of the final pharmaceutical product depends heavily on the quality of the starting materials, which is why we prioritize purity and structural accuracy in every batch.

Designed primarily for use in the synthesis of poly(ADP-ribose) polymerase inhibitors, this material serves as a foundational precursor. The high purity levels maintained during production minimize impurities that could affect subsequent reaction yields or final drug safety profiles. We understand the rigorous demands of pharmaceutical supply chains and commit to delivering materials that meet international regulatory expectations. Our production capabilities allow us to support both research-scale requirements and large-scale commercial manufacturing needs.

Technical Specifications

To ensure transparency and facilitate quality assurance protocols for our clients, we provide comprehensive technical data for 3-(4-Nitrophenyl)pyridine. The following parameters are verified through advanced analytical methods including HPLC and NMR spectroscopy. Consistency in these physical and chemical properties is essential for maintaining reproducible results in organic synthesis.

ParameterValue
CAS Number4282-46-6
Molecular FormulaC11H8N2O2
Molecular Weight200.19 g/mol
Assay (Purity)≥98.0%
Density1.252 g/cm³
Boiling Point364.6°C at 760 mmHg
Flash Point174.3°C

Industrial Applications

The primary application of 3-(4-Nitrophenyl)pyridine lies in the pharmaceutical sector, specifically as a key intermediate in the manufacturing of Niraparib. Niraparib is a significant therapeutic agent used in oncology, highlighting the importance of high-quality starting materials. Beyond this specific application, the compound is valuable in various organic synthesis routes where nitrophenyl pyridine structures are required. Its chemical stability and reactivity profile make it suitable for cross-coupling reactions and heterocyclic modifications.

  • Essential precursor for PARP inhibitor synthesis.
  • Utilized in cross-coupling reactions and heterocyclic modifications.
  • Supports research and development of new oncology treatments.
  • Compatible with standard industrial scaling processes.

Quality Assurance and Storage

We prioritize product integrity from synthesis to delivery. Each batch undergoes comprehensive analytical testing to verify identity and purity. Certificates of Analysis (COA) are provided with every shipment to ensure transparency and compliance. To maintain stability, the product should be stored in a cool, well-ventilated area away from direct sunlight and incompatible substances. Standard packaging includes 25 kg drums, with customization available to meet specific logistical requirements.

Our commitment extends beyond mere supply; we partner with clients to optimize their synthesis routes. By providing consistent quality and reliable logistics, we support the efficient production of life-saving medications. Safety data sheets are available upon request to ensure safe handling during transport and usage. For technical inquiries or bulk procurement requests, our team is ready to assist with detailed specifications and competitive pricing structures tailored to your project needs.