Intermediates

1-[3,5-Bis(trifluoromethyl)phenyl]ethanone

  • CAS No.30071-93-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity fluorinated intermediate for pharmaceutical synthesis. Reliable supply with comprehensive COA and global shipping capabilities.

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Product Technical Details

Product Overview

1-[3,5-Bis(trifluoromethyl)phenyl]ethanone is a specialized fluorinated organic compound widely recognized for its utility in advanced medicinal chemistry and pharmaceutical development. As a key building block, this substance features a distinctive aromatic structure substituted with two trifluoromethyl groups, which significantly enhances the lipophilicity and metabolic stability of downstream drug candidates. Our manufacturing process ensures consistent quality suitable for rigorous research and industrial scale synthesis.

The incorporation of fluorine atoms into organic molecules is a critical strategy in modern drug design. This specific acetophenone derivative serves as a vital precursor in the construction of complex heterocyclic systems and active pharmaceutical ingredients. By utilizing this high-grade intermediate, chemists can achieve superior bioavailability profiles in final therapeutic products. We maintain strict quality control protocols to guarantee that every batch meets international standards for purity and chemical integrity.

Key Specifications

ParameterSpecification
CAS Number30071-93-3
Molecular FormulaC10H6F6O
Molecular Weight256.14 g/mol
AppearanceLight yellow liquid
Purity (GC)≥99.0%
Boiling Point95-98 °C (15 mmHg)
Density1.422 g/cm3
Refractive Index1.4221

Industrial Applications

This fluorinated ketone is primarily employed as a pharmaceutical intermediate in the synthesis of various therapeutic agents. Its chemical reactivity allows for versatile functionalization, making it an ideal candidate for multi-step organic synthesis routes. Common applications include the development of receptor antagonists and enzyme inhibitors where metabolic stability is paramount. The electron-withdrawing nature of the trifluoromethyl groups modulates the electronic properties of the aromatic ring, facilitating specific coupling reactions required in complex molecule assembly.

Beyond pharmaceuticals, this compound finds utility in the creation of agrochemicals and advanced materials where fluorine substitution imparts desirable physical properties. Our supply chain is optimized to support both laboratory-scale research and large-scale commercial production. We provide comprehensive technical support to assist clients in integrating this material into their specific manufacturing processes efficiently.

Quality Assurance and Storage

Every shipment is accompanied by a Certificate of Analysis (COA) verifying compliance with our factory standards. Test results consistently demonstrate assay values exceeding 99.0%, with minimal impurity profiles and controlled moisture content. To maintain product stability, storage should be in a cool, dry, and well-ventilated area away from incompatible substances. Containers must remain tightly closed to prevent contamination or degradation. We recommend keeping the material away from heat sources, sparks, and open flames due to its chemical nature. Proper handling procedures ensure safety and preserve the integrity of the compound throughout its shelf life.