3,5-Bis(trifluoromethyl)phenol
- CAS No.349-58-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3,5-Bis(trifluoromethyl)phenol (CAS 349-58-6) designed for advanced organic synthesis. Reliable supply with ≥99.0% assay for pharmaceutical and agrochemical intermediates.
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Product Overview
3,5-Bis(trifluoromethyl)phenol is a highly specialized fluorinated aromatic compound that serves as a critical building block in modern organic synthesis. Characterized by the presence of two electron-withdrawing trifluoromethyl groups positioned at the meta locations on the phenol ring, this chemical intermediate offers unique reactivity profiles essential for advanced medicinal chemistry and material science applications. Our facility produces this compound under strict quality control measures to ensure consistent performance in downstream reactions.
The introduction of fluorine atoms into organic molecules is a strategic approach used to enhance metabolic stability, lipophilicity, and binding affinity in pharmaceutical candidates. As a result, this phenol derivative is frequently utilized by research laboratories and industrial manufacturers seeking to optimize the physicochemical properties of complex molecular structures. We provide this material with high purity standards to support rigorous synthetic pathways. Handling procedures should follow standard safety protocols for phenolic compounds to ensure operator safety and product integrity.
Technical Specifications
Our production process adheres to international quality standards, ensuring that every batch meets the required physical and chemical parameters. The following table outlines the key specifications for this product, verified through advanced analytical techniques such as HPLC and NMR spectroscopy. The stability of the trifluoromethyl group under various reaction conditions makes it a reliable choice for multi-step synthesis.
| Parameter | Value |
|---|---|
| CAS Number | 349-58-6 |
| Molecular Formula | C8H4F6O |
| Molecular Weight | 230.107 |
| Appearance | Colorless To Light Yellow Transparent Liquid |
| Assay | ≥99.0% |
| Melting Point | 20-21 °C |
| Boiling Point | 176.2±35.0 °C |
| Density | 1.5±0.1 G/Cm3 |
Industrial Applications
This fluorinated intermediate finds extensive utility across multiple high-value sectors. In the pharmaceutical industry, it acts as a precursor for synthesizing novel drug candidates where metabolic resistance is crucial. The strong electron-withdrawing nature of the trifluoromethyl groups modifies the acidity of the phenolic hydroxyl group, enabling specific coupling reactions that are difficult to achieve with non-fluorinated analogs.
- Medicinal Chemistry Building Block For Kinase Inhibitors
- Agrochemical Synthesis For Enhanced Pest Control Agents
- Material Science Applications In Liquid Crystal Displays
- Polymer Modification To Improve Thermal Stability
Furthermore, researchers utilize this compound in the development of advanced polymers and specialty materials where chemical resistance and durability are paramount. The versatility of this molecule allows it to be integrated into diverse synthetic routes, making it a valuable asset for innovation in chemical manufacturing. Global supply chain reliability is a key advantage of partnering with us for these specialized materials.
Quality Assurance And Storage
We are committed to delivering products that exceed industry expectations. Each shipment is accompanied by a comprehensive Certificate Of Analysis (COA) detailing the test results for purity and identity. Proper storage is essential to maintain the integrity of the chemical. We recommend storing the material in a cool, ventilated place away from direct sunlight and incompatible substances.
Packaging options include standard 200 kg drums, with flexibility to accommodate specific customer requirements for bulk orders. Our logistics team ensures safe and timely global delivery, adhering to all relevant transportation regulations for chemical goods. Contact our technical support team for detailed safety data sheets and customization options tailored to your production needs.
