Intermediates

3,5-Dichloro-2-fluoropyridine

  • CAS No.823-56-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3,5-Dichloro-2-fluoropyridine (CAS 823-56-3) designed for pharmaceutical intermediate synthesis. Available in bulk with strict quality control.

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Product Technical Details

Product Overview

3,5-Dichloro-2-fluoropyridine is a highly valued fluorinated heterocyclic compound widely utilized in the fine chemical and pharmaceutical industries. As a critical building block, this substance features a pyridine ring substituted with chlorine and fluorine atoms, offering unique reactivity profiles essential for complex organic synthesis. The presence of the fluorine atom at the 2-position significantly enhances the metabolic stability and lipophilicity of downstream molecules, making it a preferred choice for medicinal chemists designing novel therapeutic agents.

Our manufacturing process ensures consistent quality and high purity levels, adhering to strict international standards. This compound serves as a versatile intermediate for constructing more complex molecular architectures, particularly in the development of agrochemicals and pharmaceutical active ingredients. The strategic placement of halogen atoms allows for selective nucleophilic substitution reactions, facilitating efficient route synthesis for target compounds.

Technical Specifications

We maintain rigorous quality control protocols to guarantee the performance of 3,5-Dichloro-2-fluoropyridine in your production processes. Each batch is thoroughly analyzed using advanced chromatographic methods to verify purity and identity. The following table outlines the key physical and chemical properties typically associated with our premium grade material.

ParameterSpecification
CAS Number823-56-3
Molecular FormulaC5H2Cl2FN
Molecular Weight165.98 g/mol
AppearanceWhite Crystalline Powder
Purity≥98.0%
Melting Point41-43°C
Boiling Point190.2±35.0 °C at 760 mmHg
Density1.5±0.1 g/cm3
Refractive Index1.528

Industrial Applications

The primary application of 3,5-Dichloro-2-fluoropyridine lies in the synthesis of pharmaceutical intermediates. Its chemical structure allows it to act as a key precursor in the production of various bioactive molecules. The fluorine substituent is particularly valuable in drug design due to its ability to modulate electronic effects and block metabolic hot spots. Additionally, this compound finds utility in the agrochemical sector, where it contributes to the development of advanced pesticides and herbicides with improved environmental profiles.

  • Pharmaceutical Intermediate Synthesis
  • Agrochemical Active Ingredient Production
  • Fluorinated Heterocycle Construction
  • Organic Chemistry Research and Development

Quality Assurance and Safety

Safety and reliability are paramount in our supply chain. We provide a comprehensive Certificate of Analysis (COA) with every shipment, detailing batch-specific test results. Proper storage is essential to maintain the integrity of the product. It should be kept in a tightly closed container in a cool, dry, and well-ventilated area, away from incompatible substances such as strong oxidizing agents. Personnel handling this material should utilize appropriate personal protective equipment, including gloves and safety goggles, to prevent exposure.

As a global manufacturer, we are committed to supporting our partners with reliable logistics and technical expertise. Whether you require standard bulk quantities or custom synthesis solutions, our team is equipped to meet your specific production needs efficiently. Choose our 3,5-Dichloro-2-fluoropyridine for your next project and benefit from our dedication to quality, consistency, and customer satisfaction.