Intermediates

3,5-Difluoro-2-methylbenzonitrile

  • CAS No.1003708-74-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3,5-Difluoro-2-methylbenzonitrile intermediate for advanced organic synthesis. Available in bulk with comprehensive quality documentation.

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Product Technical Details

Product Overview

3,5-Difluoro-2-methylbenzonitrile is a specialized fluorinated aromatic compound designed for use in complex organic synthesis pathways. As a key building block, this nitrile derivative offers exceptional stability and reactivity, making it an essential component for pharmaceutical and agrochemical research. Our manufacturing process ensures consistent quality and high purity levels to meet the rigorous demands of modern chemical development.

The presence of fluorine atoms at the 3 and 5 positions enhances the metabolic stability and lipophilicity of downstream molecules. This characteristic is highly valued in medicinal chemistry when optimizing lead compounds for biological activity. The methyl group at the 2 position provides additional steric properties that can influence reaction selectivity during subsequent synthetic steps.

Technical Specifications

We adhere to strict quality control protocols to guarantee the integrity of every batch. The following table outlines the critical physical and chemical parameters for this product.

ParameterValue
Chemical Name3,5-Difluoro-2-methylbenzonitrile
CAS Number1003708-74-4
Molecular FormulaC8H5F2N
Molecular Weight153.13 g/mol
Purity≥99.0%
AppearanceOff-white to white crystalline powder

Industrial Applications

This compound serves as a versatile intermediate in the production of various fine chemicals. Its primary use cases include:

  • Pharmaceutical API Synthesis: Used as a precursor for developing novel therapeutic agents targeting neurological and metabolic disorders.
  • Agrochemical Development: Integrated into the structure of advanced pesticides and herbicides to improve environmental stability.
  • Material Science: Employed in the creation of specialized polymers and liquid crystal materials requiring fluorinated aromatic units.
  • Cross-Coupling Reactions: Suitable for palladium-catalyzed coupling processes due to the reactive nitrile and fluoro substituents.

Quality Assurance And Safety

Every production lot undergoes comprehensive analytical testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy. We provide a Certificate of Analysis (COA) with each shipment to verify compliance with specified purity standards. Our facility operates under strict safety management systems to ensure hazardous materials are handled correctly throughout the supply chain.

Packaging And Storage

To maintain product integrity during transit, we offer robust packaging solutions. Standard packing is 25 kg per drum, though custom packaging options are available to suit specific logistical requirements. The material should be stored in a cool, ventilated area away from direct sunlight and moisture. Proper sealing is recommended to prevent contamination or degradation over extended storage periods.

Why Partner With Us

As a global manufacturer with decades of experience, we prioritize reliability and technical support. Our team assists clients with synthesis route optimization and scale-up strategies. We offer competitive bulk pricing and ensure timely delivery to keep your research and production schedules on track. Contact us today to discuss your specific requirements for 3,5-Difluoro-2-methylbenzonitrile.