Intermediates

3',5'-Difluoroacetophenone

  • CAS No.123577-99-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3',5'-Difluoroacetophenone (CAS 123577-99-1) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and agrochemical applications.

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Product Technical Details

Product Overview

3',5'-Difluoroacetophenone is a specialized fluorinated aromatic ketone serving as a critical building block in modern organic synthesis. As a key intermediate, this compound facilitates the introduction of difluorophenyl moieties into complex molecular structures. Our manufacturing process ensures consistent quality and high purity levels, making it an ideal choice for research and industrial scale production. The strategic placement of fluorine atoms enhances the metabolic stability and lipophilicity of downstream pharmaceutical candidates.

Key Specifications

ParameterValue
Chemical Name3',5'-Difluoroacetophenone
CAS Number123577-99-1
Molecular FormulaC8H6F2O
Molecular Weight156.13 g/mol
AppearanceWhite to light yellow low melting solid
Assay≥98.0%
Melting Point34-38 °C
Boiling Point94 °C
Density1.206 g/cm3

Industrial Applications

This fluorinated intermediate is extensively utilized in the synthesis of active pharmaceutical ingredients (APIs) and agrochemical compounds. The presence of fluorine atoms often improves the bioavailability and binding affinity of drug molecules. Consequently, 3',5'-Difluoroacetophenone is frequently employed in the development of neurological therapeutics and anti-inflammatory agents. It serves as a versatile precursor for coupling reactions, condensation processes, and heterocyclic synthesis. Manufacturers in the fine chemical sector rely on this material for creating high-performance polymers and specialty materials.

Quality Assurance and Storage

We adhere to strict quality management systems to guarantee product consistency. Every batch undergoes rigorous testing via HPLC and NMR to confirm identity and purity. A Certificate of Analysis (COA) is provided with each shipment to ensure transparency and compliance. For optimal stability, store this product in a cool, ventilated place away from direct sunlight and moisture. Proper packaging in 25 kg drums or customized containers ensures safe transportation globally. Our technical support team is available to assist with synthesis routes and application guidance.

Why Choose Our Supply

  • Consistent high purity levels suitable for sensitive reactions
  • Scalable production capacity for bulk industrial requirements
  • Competitive pricing structures for long-term partnerships
  • Reliable logistics and timely delivery worldwide
  • Comprehensive documentation and regulatory support