Intermediates

3,5-Difluorobenzyl Bromide

  • CAS No.141776-91-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3,5-Difluorobenzyl Bromide (CAS 141776-91-2) is a essential fluorinated building block for pharmaceutical and agrochemical synthesis, available in bulk quantities.

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Product Technical Details

Product Overview

3,5-Difluorobenzyl Bromide represents a critical fluorinated building block within the realm of advanced organic synthesis and chemical manufacturing. As a halogenated aromatic compound, this substance serves as a versatile alkylating agent, enabling chemists to introduce the 3,5-difluorobenzyl moiety into complex molecular structures with high precision. The presence of fluorine atoms significantly enhances the metabolic stability and lipophilicity of downstream products, making this intermediate highly sought after in the development of novel pharmaceutical agents and agrochemical formulations. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and industrial scale production requirements.

We understand the importance of supply chain stability for critical intermediates. Our facility maintains robust inventory levels to support continuous production schedules for our global partners. Whether you are scaling up from laboratory research to pilot plant operations or full commercial manufacturing, our team provides the reliability and technical expertise needed to ensure your projects proceed without interruption. Quality consistency is our primary commitment to every client.

Chemical Properties and Reactivity

This colorless clear liquid exhibits distinct physical characteristics that facilitate its handling and integration into various reaction pathways. The bromine atom at the benzylic position provides a reactive site for nucleophilic substitution reactions, allowing for the formation of carbon-carbon, carbon-nitrogen, and carbon-oxygen bonds efficiently. The difluoro substitution pattern on the benzene ring influences the electronic properties of the molecule, offering unique reactivity profiles compared to non-fluorinated analogs. Careful control of storage conditions is recommended to maintain stability, as benzyl bromides can be sensitive to moisture and light over extended periods. The compound density and refractive index serve as key quality control indicators during batch verification processes.

Key Advantages

  • High purity grade exceeding 99.0 percent by gas chromatography analysis
  • Consistent batch-to-batch reproducibility for large scale manufacturing
  • Enhanced reactivity due to strategic fluorine placement on the ring
  • Comprehensive documentation including Certificate of Analysis and MSDS
  • Flexible packaging options to suit diverse logistical requirements

Industrial Applications

The primary application of 3,5-Difluorobenzyl Bromide lies in the synthesis of fine chemicals and active pharmaceutical ingredients. It is frequently utilized in the preparation of kinase inhibitors, receptor modulators, and other therapeutic candidates where fluorine substitution is required to optimize pharmacokinetic properties. In the agrochemical sector, this intermediate contributes to the development of herbicides and pesticides with improved environmental profiles and efficacy. Additionally, materials science researchers employ this compound in the creation of specialized polymers and liquid crystals for advanced display technologies. Our global supply chain supports diverse industries requiring reliable access to high quality fluorinated intermediates for innovation and product development.

Quality Assurance and Packaging

We adhere to strict quality management systems to ensure every drum meets specified parameters before shipment. Each production batch undergoes rigorous testing for purity, identity, and physical constants using validated analytical methods. Standard packaging includes 200 kg drums, though we offer flexible solutions tailored to specific customer logistics and volume requirements. Storage in a cool, ventilated area away from incompatible substances is essential for maintaining product integrity during transit and warehousing. Our team provides full technical support and safety data documentation to facilitate safe handling and regulatory compliance across international borders. Partner with us for a reliable source of premium chemical intermediates.

Technical Specifications

ParameterSpecification
CAS Number141776-91-2
Molecular FormulaC7H5BrF2
Molecular Weight207.02 g/mol
AppearanceColorless clear liquid
Purity (GC)≥99.0%
Density1.6 g/cm3
Boiling Point65°C
Refractive Index1.521