Intermediates

3,5-Difluorophenylacetic Acid

  • CAS No.105184-38-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3,5-Difluorophenylacetic Acid (CAS 105184-38-1) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical and chemical manufacturing.

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Product Technical Details

Product Overview

3,5-Difluorophenylacetic Acid is a specialized fluorinated aromatic acid that serves as a vital building block in modern organic chemistry. This compound is characterized by the presence of two fluorine atoms at the meta positions of the phenyl ring, which significantly influences its electronic properties and reactivity. Our facility produces this intermediate using advanced synthesis routes to ensure consistent quality and high purity levels suitable for demanding research and industrial applications.

As a key component in the development of complex molecular structures, this acid offers excellent stability and reactivity profiles. The introduction of fluorine atoms often enhances the metabolic stability and lipophilicity of downstream products, making this intermediate highly valuable in the creation of novel chemical entities. We maintain rigorous manufacturing standards to support global supply chains for pharmaceutical and agrochemical sectors.

Technical Specifications

The physical and chemical properties of 3,5-Difluorophenylacetic Acid are critical for its performance in synthesis reactions. Our quality control team verifies every batch against strict parameters to ensure compliance with international standards. The following table outlines the key technical characteristics of this product.

ParameterValue
CAS Number105184-38-1
Molecular FormulaC8H6F2O2
Molecular Weight172.13 g/mol
AppearanceWhite powder
Purity (Assay)≥98.0%
Melting Point68-70 °C
Boiling Point245.0 °C at 760 mmHg
Density1.4 g/cm3

Quality Assurance

We understand that consistency is paramount in chemical manufacturing. Every production lot undergoes comprehensive testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy. This ensures that the impurity profile remains within acceptable limits and that the structural integrity of the molecule is preserved. Customers receive a detailed Certificate of Analysis (COA) with each shipment, providing full transparency regarding the quality of the material supplied.

Industrial Applications

This fluorinated intermediate is primarily utilized in the synthesis of more complex organic molecules. Its specific substitution pattern makes it suitable for various coupling reactions and functional group transformations. Common application areas include:

  • Pharmaceutical intermediate synthesis for novel drug discovery programs.
  • Agrochemical development requiring enhanced metabolic stability.
  • Material science research involving fluorinated polymers.
  • Custom organic synthesis projects requiring specific aromatic building blocks.

Storage and Handling

To maintain the integrity of 3,5-Difluorophenylacetic Acid, proper storage conditions are essential. The product should be kept in a cool, ventilated area away from direct sunlight and moisture. Containers must be tightly sealed when not in use to prevent degradation. We recommend standard laboratory safety protocols during handling, including the use of appropriate personal protective equipment. Bulk packaging options are available, including 25 kg drums, with custom packaging solutions available upon request to meet specific logistical requirements.