3,5-Difluorophenylboronic acid
- CAS No.156545-07-2
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3,5-Difluorophenylboronic acid (CAS 156545-07-2) designed for advanced organic synthesis and pharmaceutical intermediate production.
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Product Overview
3,5-Difluorophenylboronic acid is a highly specialized organoboron compound that serves as a critical building block in modern medicinal chemistry and agrochemical development. Characterized by the presence of two fluorine atoms at the meta positions of the phenyl ring, this molecule offers unique electronic properties that enhance reactivity in cross-coupling reactions. Our facility produces this compound under strict quality control standards to ensure consistent performance in complex synthetic pathways.
As a leading global manufacturer, we understand the demanding requirements of pharmaceutical research and industrial scale-up. This boronic acid derivative is particularly valued for its stability and solubility profile, making it an ideal candidate for Suzuki-Miyaura coupling reactions. These reactions are fundamental in constructing biaryl structures found in numerous active pharmaceutical ingredients (APIs) and functional materials.
Technical Specifications
We maintain rigorous testing protocols to guarantee that every batch meets or exceeds industry standards. The following table outlines the key physical and chemical parameters verified during our quality assurance process.
| Parameter | Specification |
|---|---|
| CAS Number | 156545-07-2 |
| Molecular Formula | C6H5BF2O2 |
| Molecular Weight | 157.91 g/mol |
| Appearance | White to light yellow powder |
| Assay (Purity) | ≥99.0% |
| Moisture Content | ≤0.2% |
| Melting Point | 210-217°C |
| Density | 1.35 g/cm³ |
Industrial Applications
The versatility of 3,5-Difluorophenylboronic acid extends across multiple high-value sectors. In the pharmaceutical industry, it is frequently employed in the late-stage functionalization of drug candidates. The fluorine substituents can significantly improve metabolic stability and bioavailability of the final drug product. Additionally, this compound is utilized in the synthesis of liquid crystals and organic electronic materials where precise electronic tuning is required.
- Pharmaceutical intermediate synthesis for kinase inhibitors.
- Agrochemical development for enhanced crop protection agents.
- Material science applications in OLED and polymer manufacturing.
- Research and development for novel catalytic processes.
Quality Assurance and Storage
To preserve the integrity of this sensitive chemical, proper storage conditions are essential. We recommend keeping the product in a cool, ventilated environment away from direct sunlight and moisture sources. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing batch-specific test results. Our packaging options include 25 kg drums, with customization available to meet specific logistical requirements. By choosing our supply chain, partners gain access to reliable inventory levels and technical support for process optimization.
