3,5-Difluoropyridine
- CAS No.71902-33-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3,5-Difluoropyridine (CAS 71902-33-5) is a vital fluorinated heterocyclic intermediate designed for pharmaceutical research and industrial organic synthesis applications.
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Product Overview
3,5-Difluoropyridine represents a critical class of fluorinated heterocyclic compounds extensively utilized in modern medicinal chemistry and advanced organic synthesis. As a key building block, this compound features a pyridine ring substituted with fluorine atoms at the 3 and 5 positions, offering unique electronic and steric properties that enhance the metabolic stability and lipophilicity of downstream drug candidates. Our manufacturing process ensures consistent quality suitable for large-scale pharmaceutical production and research development.
The strategic incorporation of fluorine into heterocyclic scaffolds is a cornerstone of contemporary drug design. This specific isomer provides versatile reactivity for nucleophilic aromatic substitution and cross-coupling reactions, making it an indispensable tool for chemists aiming to optimize lead compounds. We supply this material with rigorous quality control standards to support your innovation pipeline.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 3,5-Difluoropyridine |
| CAS Number | 71902-33-5 |
| Molecular Formula | C5H3F2N |
| Molecular Weight | 115.08 g/mol |
| Appearance | Yellow liquid |
| Purity | ≥99.0% |
| Boiling Point | 92-93°C |
| Density | 1.268 g/cm3 |
| Refractive Index | 1.437 |
| Flash Point | 9°C |
Industrial Applications
This fluorinated pyridine derivative serves as a fundamental intermediate in the synthesis of various active pharmaceutical ingredients (APIs). Its high reactivity allows for efficient functionalization, enabling the creation of complex molecular architectures required for novel therapeutics. Beyond pharmaceuticals, it finds utility in agrochemical research and material science where heterocyclic stability is paramount.
- Essential building block for kinase inhibitors and receptor modulators.
- Used in cross-coupling reactions such as Suzuki and Buchwald-Hartwig amination.
- Facilitates the development of metabolically stable drug candidates.
- Supports large-scale manufacturing processes with consistent batch quality.
Quality Assurance and Storage
We adhere to strict quality management systems to ensure every drum meets the specified purity levels. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing physical and chemical properties. Proper storage is essential to maintain product integrity. Store in a tightly closed container in a cool, dry, and well-ventilated area away from incompatible materials. Our packaging options include 25kg drums designed for safe global transportation.
