3-Acetyl-2,5-dichlorothiophene
- CAS No.36157-40-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Acetyl-2,5-dichlorothiophene (CAS 36157-40-1) designed for pharmaceutical synthesis. Ideal intermediate for Brinzolamide production with ≥98% assay.
Request Bulk PricingProduct Technical Details
Product Overview
Welcome to our specialized range of advanced pharmaceutical intermediates, featuring high-quality 3-Acetyl-2,5-dichlorothiophene. This heterocyclic compound serves as a critical building block in the modern medicinal chemistry landscape. Our facility is dedicated to producing fine chemicals that meet the rigorous demands of global pharmaceutical manufacturing. We understand that the purity and consistency of raw materials directly impact the efficacy and safety of final therapeutic products. Therefore, every batch undergoes strict quality control protocols to ensure compliance with international standards.
Technical Specifications
| Parameter | Specification |
|---|---|
| Product Name | 3-Acetyl-2,5-dichlorothiophene |
| CAS Number | 36157-40-1 |
| Molecular Formula | C6H4Cl2OS |
| Molecular Weight | 195.07 g/mol |
| Purity (HPLC) | ≥98.0% |
| Appearance | White to pale yellow crystalline solid |
| Moisture Content | ≤0.5% |
| Total Impurities | ≤0.5% |
Physical and Chemical Properties
This thiophene derivative exhibits stable chemical characteristics suitable for multi-step organic synthesis. The compound presents as a crystalline solid with a melting point range between 37 and 40 degrees Celsius. It possesses a density of approximately 1.452 g/cm3 and a boiling point of 120 to 122 degrees Celsius under reduced pressure (4mm). The refractive index is recorded at 1.575, indicating high optical consistency. With a flash point exceeding 230 degrees Fahrenheit, the material maintains favorable safety profiles during standard handling and processing conditions. These physical properties make it an ideal candidate for various reaction environments requiring thermal stability.
Industrial Applications
Primarily utilized within the pharmaceutical sector, this chemical acts as a key intermediate in the synthetic pathway of specific therapeutic agents. It is notably employed in the production pipeline for Brinzolamide, a carbonic anhydrase inhibitor used in ophthalmic treatments. Beyond this specific application, the versatile dichlorothiophene structure allows for further functionalization in the development of novel drug candidates. Researchers and process chemists value this intermediate for its reactivity and reliability in forming complex molecular architectures. Our supply supports both pilot-scale research and large-scale commercial manufacturing needs.
Quality Assurance and Packaging
Quality is the cornerstone of our operation. Each production lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing test results against specified parameters. We employ advanced analytical techniques, including HPLC and NMR, to verify structural integrity and purity levels. The product is packaged in 25kg cardboard drums to ensure protection during transit, though custom packaging solutions are available upon request. Proper storage is essential to maintain product integrity. We recommend storing the material in a cool, dry, and well-closed container, protected from moisture and strong light or heat sources. Our logistics team ensures global shipping compliance, delivering reliable supply chain solutions to partners worldwide.
