3-Amino-2-Bromo-5-Fluoropyridine
- CAS No.884495-03-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Amino-2-Bromo-5-Fluoropyridine (CAS 884495-03-8) designed for advanced pharmaceutical synthesis. Reliable supply with strict quality control for global research and production needs.
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Product Overview
3-Amino-2-Bromo-5-Fluoropyridine is a highly specialized heterocyclic building block extensively utilized in modern medicinal chemistry and organic synthesis. As a halogenated pyridine derivative, this compound offers exceptional reactivity profiles suitable for constructing complex molecular architectures. Our manufacturing process ensures consistent quality, making it an ideal candidate for researchers and industrial chemists focusing on novel drug discovery and development pipelines.
The presence of both bromine and fluorine substituents on the pyridine ring provides versatile handles for cross-coupling reactions and nucleophilic substitutions. This dual functionality allows chemists to selectively modify the molecular structure at specific positions, facilitating the efficient synthesis of targeted pharmaceutical active ingredients. We prioritize purity and structural integrity in every batch produced.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 3-Amino-2-Bromo-5-Fluoropyridine |
| CAS Number | 884495-03-8 |
| Molecular Formula | C5H4BrFN2 |
| Molecular Weight | 191.00 g/mol |
| Purity | ≥99.0% (HPLC) |
| Melting Point | 114-116 °C |
| Appearance | Off-white to Pale Yellow Solid |
| Packing | 25kg/drum or customized |
Industrial Applications
This chemical intermediate serves as a critical precursor in the synthesis of various therapeutic agents. Its primary applications span across multiple stages of pharmaceutical development, from early-stage lead optimization to large-scale commercial manufacturing. The compound is particularly valuable in the production of kinase inhibitors and other small molecule drugs where heterocyclic cores are essential for biological activity.
- Utilized in palladium-catalyzed cross-coupling reactions such as Suzuki and Buchwald-Hartwig aminations.
- Employed in the construction of fused heterocyclic systems for oncology and CNS drug candidates.
- Serves as a key building block for agrochemical research and advanced material science applications.
- Compatible with diverse synthetic routes requiring high regioselectivity and yield.
Quality Assurance and Storage
Quality control is paramount in our production facility. Each batch of 3-Amino-2-Bromo-5-Fluoropyridine undergoes rigorous testing using advanced analytical techniques including High-Performance Liquid Chromatography (HPLC), Nuclear Magnetic Resonance (NMR), and Mass Spectrometry (MS). We provide a comprehensive Certificate of Analysis (COA) with every shipment to verify compliance with specified purity standards and physical properties.
For optimal stability, the product should be stored in a tightly closed container within a cool, dry, and well-ventilated area. Protection from moisture and direct sunlight is recommended to maintain chemical integrity over extended periods. Our packaging solutions are designed to prevent contamination during transit, ensuring the material arrives in pristine condition for immediate use in your laboratory or production line. We support global logistics with reliable shipping methods tailored to hazardous chemical regulations.
