Intermediates

3'-Amino-2'-Hydroxyacetophenone Hydrochloride

  • CAS No.90005-55-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity pharmaceutical intermediate used in the synthesis of Ranlukast. Available in bulk quantities with strict quality control and comprehensive documentation.

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Product Technical Details

Product Overview

3'-Amino-2'-Hydroxyacetophenone Hydrochloride is a specialized organic compound designed for advanced pharmaceutical synthesis. As a critical building block, this chemical serves as a key precursor in the manufacturing of complex therapeutic agents, including leukotriene antagonists. Our facility produces this intermediate under stringent quality management systems to ensure consistency and reliability for downstream processing.

This compound is characterized by its specific structural configuration, which facilitates efficient coupling reactions in multi-step synthesis pathways. We understand the importance of purity in pharmaceutical manufacturing, which is why our production process emphasizes rigorous purification steps to minimize impurities that could affect final drug efficacy.

Technical Specifications

ParameterValue
Chemical Name3'-Amino-2'-Hydroxyacetophenone Hydrochloride
CAS Number90005-55-3
Molecular FormulaC8H10ClNO2
Molecular Weight187.62 g/mol
AppearanceLight Brown Solid
Purity≥99.0%
Melting Point156-160°C
Boiling Point287.2°C at 760 mmHg
Flash Point127.5°C

Applications and Usage

The primary application of this material lies in the pharmaceutical sector, specifically as an intermediate for the synthesis of Ranlukast. Its chemical properties make it suitable for various organic transformation reactions required in the construction of active pharmaceutical ingredients (APIs). Researchers and process chemists utilize this building block to achieve high yields in nucleophilic substitution and condensation reactions.

Beyond its specific use in leukotriene antagonist synthesis, this compound demonstrates versatility in medicinal chemistry research. It serves as a valuable tool for developing new therapeutic candidates where amino-hydroxy phenyl structures are required. Our technical team supports clients with guidance on optimal reaction conditions to maximize efficiency.

Quality Assurance and Storage

We maintain a robust quality control framework to guarantee that every batch meets the specified purity standards. Each shipment is accompanied by a Certificate of Analysis (COA) detailing test results against established specifications. Our commitment to quality ensures that your production processes remain uninterrupted and compliant with regulatory expectations.

  • Stored in tightly closed containers to prevent moisture absorption.
  • Kept in a cool, dry, and well-ventilated area away from incompatible substances.
  • Packaged in 25kg cardboard drums or according to customer requirements.
  • Handled with appropriate personal protective equipment during transfer.

For bulk orders or custom synthesis requirements, our global logistics network ensures timely delivery while maintaining product integrity throughout the supply chain. Contact our sales team for detailed pricing and technical documentation.