Intermediates

3-Amino-2-methylbenzoic acid

  • CAS No.52130-17-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Amino-2-methylbenzoic acid designed for pharmaceutical intermediate synthesis. Reliable supply with strict quality control and global logistics support.

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Product Technical Details

Product Overview

3-Amino-2-methylbenzoic acid is a specialized organic compound widely recognized for its critical role in the synthesis of advanced pharmaceutical agents. As a substituted benzoic acid derivative, this chemical features both amino and methyl functional groups on the aromatic ring, providing unique reactivity profiles essential for complex medicinal chemistry workflows. Our facility produces this intermediate under strict Good Manufacturing Practice (GMP) guidelines to ensure consistency and reliability for downstream API production.

We understand that the quality of starting materials directly impacts the efficacy and safety of final therapeutic products. Therefore, our 3-Amino-2-methylbenzoic acid undergoes rigorous purification processes to achieve high assay values suitable for sensitive synthetic routes. This product serves as a vital building block in the construction of heterocyclic structures found in various modern medications.

Chemical Properties and Specifications

The molecular structure of this compound allows for versatile chemical transformations, including amidation and esterification reactions. To support our partners in process development, we maintain tight control over physical parameters such as melting point and moisture content. The following table outlines the key technical specifications guaranteed with every batch:

ParameterSpecification
AppearanceOff-white to yellowish powder
Assay (HPLC)≥98.0%
Moisture Content≤0.5%
Melting Point182-186°C
Molecular FormulaC8H9NO2
Molecular Weight151.163
CAS Number52130-17-3

Quality Assurance and Control

Quality is the cornerstone of our manufacturing philosophy. Each production lot of 3-Amino-2-methylbenzoic acid is subjected to comprehensive analytical testing using state-of-the-art instrumentation, including High-Performance Liquid Chromatography (HPLC) and Gas Chromatography (GC). These tests verify purity levels and identify any potential impurities that could interfere with subsequent synthesis steps. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full transparency and traceability from our reactor to your laboratory.

Our quality management system is designed to meet international standards, facilitating smooth regulatory filings for our clients. We maintain batch records and stability data to support long-term supply agreements. By minimizing batch-to-batch variability, we help pharmaceutical manufacturers optimize their yields and reduce production costs associated with reprocessing or failed batches.

Industrial Applications and Synthesis

This chemical intermediate is primarily utilized in the pharmaceutical industry for the synthesis of complex therapeutic agents. It acts as a precursor in the construction of quinazolinone and related heterocyclic scaffolds. Specifically, it is known for its utility in the manufacturing process of immunomodulatory compounds. The presence of the ortho-methyl group influences the steric hindrance during coupling reactions, offering chemists precise control over regioselectivity.

Beyond pharmaceuticals, this compound may find applications in agrochemical research and fine chemical synthesis where substituted aniline derivatives are required. Our technical team is available to assist with scale-up queries, providing data on solubility, reaction kinetics, and safe handling procedures to ensure smooth integration into your existing manufacturing processes.

Packaging, Storage, and Safety

To preserve product integrity during transit, 3-Amino-2-methylbenzoic acid is packaged in durable 25 kg drums lined with moisture-resistant materials. Custom packaging solutions are available upon request to accommodate specific logistical needs. Proper storage is essential to maintain stability; we recommend keeping the material in a cool, ventilated area away from direct sunlight and incompatible substances.

Safety is paramount when handling organic acids and amines. Personnel should utilize appropriate personal protective equipment (PPE), including gloves and eye protection, during handling operations. Our safety data sheets (SDS) provide comprehensive information on hazard identification, first aid measures, and disposal guidelines. By choosing us as your partner, you gain access to a reliable supply chain committed to safety, quality, and performance excellence.