Intermediates

3-Amino-5-Bromo-2-Methoxypyridine

  • CAS No.884495-39-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Amino-5-Bromo-2-Methoxypyridine (CAS 884495-39-0) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical research.

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Product Technical Details

Product Overview

3-Amino-5-Bromo-2-Methoxypyridine is a specialized heterocyclic compound that serves as a critical building block in modern medicinal chemistry and organic synthesis. Characterized by its unique pyridine ring structure substituted with amino, bromo, and methoxy groups, this molecule offers versatile reactivity for complex chemical transformations. Our facility produces this intermediate under stringent quality management systems to ensure consistency and reliability for research and development purposes.

The presence of the bromine atom at the fifth position facilitates various cross-coupling reactions, such as Suzuki, Heck, or Buchwald-Hartwig couplings, making it an invaluable asset for constructing diverse molecular architectures. Meanwhile, the amino and methoxy functionalities provide additional handles for further derivatization, allowing chemists to explore a wide range of structural analogues efficiently.

Technical Specifications

We adhere to rigorous analytical standards to guarantee the quality of every batch. Each production lot undergoes comprehensive testing using advanced instrumentation including HPLC, NMR, and Mass Spectrometry. The following table outlines the key physical and chemical parameters associated with this product:

ParameterSpecification
CAS Number884495-39-0
Molecular FormulaC6H7BrN2O
Molecular Weight203.037 g/mol
AppearanceLight yellow to dark brown solid
Assay (Purity)≥98.0%
Moisture Content≤1.0%
Melting Point53-55 °C
Boiling Point284.5±35.0 °C at 760 mmHg
Density1.6±0.1 g/cm3

Industrial Applications

This pyridine derivative is primarily utilized as a key intermediate in the synthesis of pharmaceutical agents and agrochemical compounds. Its structural features make it particularly suitable for developing kinase inhibitors and other therapeutic candidates targeting specific biological pathways. In industrial settings, it supports the manufacturing of fine chemicals where high precision and purity are paramount.

Researchers value this compound for its stability and solubility profile, which simplifies handling during multi-step synthesis routes. Whether used in academic laboratories for method development or in large-scale production facilities for process optimization, 3-Amino-5-Bromo-2-Methoxypyridine delivers consistent performance. It acts as a foundational element for creating more complex heterocyclic systems required in next-generation drug discovery programs.

Quality Assurance and Storage

Quality is the cornerstone of our manufacturing process. We implement a comprehensive Quality Assurance protocol that covers raw material sourcing, in-process controls, and final product verification. Every shipment is accompanied by a Certificate of Analysis (COA) detailing the test results against specified parameters. This transparency ensures that our clients can integrate this material into their workflows with confidence.

For optimal stability, the product should be stored in a cool, ventilated place away from direct sunlight and moisture. We offer flexible packaging options, including standard 25 kg drums, to accommodate various logistical requirements. Custom packaging solutions are also available upon request to meet specific customer needs. Our global distribution network ensures timely delivery while maintaining the integrity of the chemical throughout transit.