3-Amino-5-fluoropyridine
- CAS No.210169-05-4
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Amino-5-fluoropyridine designed for pharmaceutical intermediate synthesis. Available in bulk with comprehensive quality documentation.
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Product Overview
3-Amino-5-fluoropyridine is a specialized heterocyclic building block extensively utilized in modern medicinal chemistry and organic synthesis. As a fluorinated pyridine derivative, this compound serves as a critical precursor for the development of advanced pharmaceutical agents. The introduction of a fluorine atom at the fifth position of the pyridine ring significantly enhances the metabolic stability and bioavailability of resulting drug candidates, making it a valuable asset in drug discovery pipelines.
Our manufacturing facility adheres to strict quality management systems to ensure consistent batch-to-batch reliability. We understand the precise requirements of research laboratories and large-scale production units, delivering material that meets rigorous purity standards. This product is ideal for chemists seeking reliable starting materials for complex molecular constructions.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 3-Amino-5-fluoropyridine |
| CAS Number | 210169-05-4 |
| Molecular Formula | C5H5FN2 |
| Molecular Weight | 112.11 g/mol |
| Purity | ≥99.0% |
| Appearance | White-like solids |
| Melting Point | 86°C |
| Boiling Point | 217.1±20.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Refractive Index | 1.554 |
Applications & Advantages
This fluorinated amine is predominantly employed as a key intermediate in the synthesis of kinase inhibitors, antiviral agents, and other therapeutic compounds. The electron-withdrawing nature of the fluorine substituent allows for unique reactivity profiles during nucleophilic substitution and cross-coupling reactions. Our supply chain ensures that clients receive material suitable for both early-stage discovery and process development.
- High chemical purity ensures minimal side reactions during synthesis.
- Optimized for use in palladium-catalyzed coupling reactions.
- Enhanced metabolic stability for downstream pharmaceutical applications.
- Consistent physical properties support reproducible experimental results.
- Available in scalable quantities to support commercial manufacturing.
Storage & Handling
To maintain optimal quality, 3-Amino-5-fluoropyridine should be stored in a tightly closed container within a cool, dry, and well-ventilated area. Protection from moisture and direct sunlight is recommended to prevent degradation. Standard laboratory safety protocols should be followed during handling, including the use of appropriate personal protective equipment. We provide comprehensive documentation, including Certificates of Analysis (COA), to support regulatory compliance and quality assurance processes for all global shipments.
