3-(Benzoylthio)-2-methylpropanoic acid
- CAS No.74431-50-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity pharmaceutical intermediate essential for the synthesis of Zofenopril. Available in bulk quantities with strict quality control and global shipping capabilities.
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Product Overview
3-(Benzoylthio)-2-methylpropanoic acid is a specialized organic compound recognized for its critical role in the pharmaceutical industry. As a sulfur-containing carboxylic acid derivative, this substance serves as a vital building block in the multistep synthesis of advanced cardiovascular medications. Our manufacturing process ensures exceptional chemical stability and consistency, making it a reliable choice for large-scale API production. We adhere to rigorous quality standards to meet the demanding requirements of global pharmaceutical clients.
This compound is characterized by its distinct molecular structure, which facilitates specific chemical transformations required in modern drug development. The presence of the benzoylthio group enhances its reactivity profile, allowing for efficient coupling reactions during the synthesis process. Our facility employs state-of-the-art technology to maintain high purity levels, ensuring that each batch meets or exceeds industry specifications for pharmaceutical intermediates.
Technical Specifications
Quality and precision are paramount in the production of fine chemical intermediates. The following table outlines the key physical and chemical properties of our product. Each parameter is meticulously tested using validated analytical methods to guarantee performance in downstream applications.
| Parameter | Value |
|---|---|
| Chemical Name | 3-(Benzoylthio)-2-methylpropanoic acid |
| CAS Number | 74431-50-8 |
| Molecular Formula | C11H12O3S |
| Molecular Weight | 224.276 g/mol |
| Appearance | White needle crystal |
| Assay (Purity) | ≥98.0% |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 367.5±34.0 °C at 760 mmHg |
| Flash Point | 176.0±25.7 °C |
Industrial Applications
The primary application of this intermediate lies in the synthesis of Zofenoprilat and its calcium salt, Zofenopril calcium. These downstream products are well-known angiotensin-converting enzyme (ACE) inhibitors used in the management of hypertension and heart failure. By providing a high-quality precursor, we support the efficient manufacturing of these life-saving medications. The high purity of our intermediate minimizes impurity carryover, simplifying the purification steps in the final API production.
Beyond its specific use in ACE inhibitor synthesis, this compound demonstrates versatility in organic chemistry laboratories. It can be utilized in various sulfanyl substitution reactions and serves as a valuable reference standard for analytical development. Our technical team is available to provide guidance on optimal reaction conditions and integration into existing synthesis routes.
Quality Assurance and Packaging
We understand that consistency is key in pharmaceutical supply chains. Every production batch undergoes comprehensive testing, including HPLC analysis and spectral confirmation. A Certificate of Analysis (COA) is provided with each shipment to document compliance with specified parameters. Our quality management system is designed to trace every step of the manufacturing process, ensuring full transparency and accountability.
Standard packaging consists of 25 kg drums, which are designed to protect the product from moisture and physical damage during transit. However, we recognize that different clients have varying logistical needs. Therefore, we offer custom packaging solutions upon request to align with your specific handling and storage requirements. Our logistics partners ensure timely delivery to major industrial hubs worldwide.
Storage and Handling
To maintain the integrity of 3-(Benzoylthio)-2-methylpropanoic acid, proper storage conditions are essential. The product should be stored in a cool, ventilated place away from direct sunlight and sources of ignition. Containers must be kept tightly closed when not in use to prevent exposure to atmospheric moisture. Personnel handling this material should follow standard safety protocols, including the use of appropriate personal protective equipment. By adhering to these guidelines, users can ensure the long-term stability and safety of the chemical inventory.
