3-Bromo-1-phenyl-5-(pyridin-2-yl)pyridin-2-one

Product Overview

3-Bromo-1-phenyl-5-(pyridin-2-yl)pyridin-2-one is a specialized organic compound serving as a critical building block in modern pharmaceutical chemistry. Identified by CAS number 381248-06-2, this substance is predominantly utilized as a key intermediate in the manufacturing process of advanced neurological therapeutics. Our facility ensures that every batch meets rigorous international standards for purity and consistency, supporting large-scale production requirements for global pharmaceutical partners.

The chemical structure features a brominated pyridinone core linked to a phenyl and pyridyl group, providing unique reactivity profiles essential for complex multi-step synthesis routes. This molecular architecture allows for precise functionalization, making it an invaluable asset for medicinal chemists developing novel antiepileptic agents and related central nervous system medications.

Technical Specifications

Industrial Applications

This compound is primarily recognized for its role as a precursor in the synthesis of Perampanel, a widely prescribed antiepileptic drug. The high level of regioselectivity and stability offered by this intermediate ensures efficient downstream processing, minimizing impurities in the final active pharmaceutical ingredient (API). Beyond this specific application, the structural motifs present in this molecule make it suitable for broader research into pyridinone derivatives and heterocyclic chemistry.

Our manufacturing process is designed to maintain strict control over reaction conditions, ensuring minimal batch-to-batch variation. This reliability is crucial for clients who require consistent material properties for regulatory filings and commercial production scales. We support both standard specifications and custom synthesis requests tailored to specific project needs.

Quality Assurance and Logistics

Quality control is paramount in our operations. Each production lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to good manufacturing practices to ensure product safety and traceability throughout the supply chain.

Regarding logistics, the product is packaged in 25 kg drums or according to specific customer requirements to ensure stability during transit. Storage recommendations include keeping the material in a cool, ventilated environment away from direct sunlight and moisture. As a global manufacturer, we offer competitive bulk pricing and reliable shipping solutions to facilitate seamless integration into your production workflow.