Intermediates

3-Bromo-2-chloro-5-(trifluoromethyl)pyridine

  • CAS No.71701-92-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Bromo-2-chloro-5-(trifluoromethyl)pyridine (CAS 71701-92-3) for advanced organic synthesis. Reliable supply with COA.

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Product Technical Details

Product Overview

3-Bromo-2-chloro-5-(trifluoromethyl)pyridine is a highly specialized halogenated pyridine derivative designed for complex organic synthesis applications. This compound features a unique substitution pattern with bromine, chlorine, and trifluoromethyl groups on the pyridine ring, making it an invaluable building block for pharmaceutical and agrochemical research. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding synthetic routes.

As a key intermediate, this chemical facilitates various cross-coupling reactions and nucleophilic substitutions. The presence of the trifluoromethyl group enhances metabolic stability and lipophilicity in final drug candidates, while the halogen atoms provide versatile sites for further functionalization. We supply this material globally to research institutions and industrial manufacturers.

Technical Specifications

ParameterValue
CAS Number71701-92-3
Molecular FormulaC6H2BrClF3N
Molecular Weight260.439 g/mol
Purity (Assay)≥98.0%
AppearanceOff-white to pale yellow solid
Melting Point28-32℃
Boiling Point210.5±35.0 °C at 760 mmHg
Density1.8±0.1 g/cm3

Industrial Applications

This pyridine derivative serves primarily as a critical intermediate in the synthesis of advanced pharmaceutical APIs and agrochemical active ingredients. Its structural properties allow chemists to introduce specific functional groups with high precision. Common applications include the development of kinase inhibitors, antifungal agents, and herbicides where fluorinated heterocycles are required.

  • Pharmaceutical intermediate for novel drug discovery
  • Building block for fluorinated agrochemicals
  • Reagent for cross-coupling reactions such as Suzuki or Buchwald
  • Component in material science for organic electronics

Quality Assurance and Packaging

We adhere to strict quality control protocols to ensure every batch meets the specified purity standards. Each shipment is accompanied by a Certificate of Analysis (COA) detailing comprehensive test results. Our packaging solutions are designed to maintain product integrity during transit and storage.

Standard packaging includes 25 kg drums, though we accommodate custom packaging requirements based on client needs. Proper storage in a cool, ventilated area away from moisture and direct sunlight is recommended to preserve stability. Our logistics team ensures safe and timely global delivery.