3-Bromo-2-Fluorobenzotrifluoride
- CAS No.144584-67-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Bromo-2-Fluorobenzotrifluoride (CAS 144584-67-8) is a key fluorinated building block for pharmaceutical synthesis, available in bulk quantities with strict quality control.
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Product Overview
3-Bromo-2-Fluorobenzotrifluoride represents a critical class of fluorinated aromatic intermediates essential for modern organic synthesis and medicinal chemistry. Identified by the unique CAS registry number 144584-67-8, this compound features a strategically substituted benzene ring containing both bromine and fluorine atoms alongside a trifluoromethyl group. This specific arrangement of halogens provides exceptional reactivity profiles, making it an invaluable precursor for the development of advanced pharmaceutical agents, agrochemicals, and specialized functional materials.
Our manufacturing process ensures that every batch meets rigorous international standards for chemical purity and consistency. The presence of the trifluoromethyl moiety significantly enhances the metabolic stability and lipophilicity of downstream molecules, which is a highly sought-after characteristic in drug discovery programs. As a dedicated supplier of fine chemicals, we understand the critical nature of supply chain reliability for research and production facilities globally.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 3-Bromo-2-Fluorobenzotrifluoride |
| CAS Number | 144584-67-8 |
| Molecular Formula | C7H3BrF4 |
| Molecular Weight | 242.996 g/mol |
| Appearance | Light Yellow Liquid |
| Purity | ≥99.0% |
| Boiling Point | 168-169°C |
| Density | 1.72 g/cm3 |
| Refractive Index | 1.464 |
| Flash Point | >100°C |
Industrial Applications and Advantages
This fluorinated intermediate serves as a versatile building block in cross-coupling reactions, such as Suzuki, Heck, and Buchwald-Hartwig aminations. The selective reactivity of the bromo and fluoro substituents allows chemists to perform sequential functionalizations with high precision. This capability is particularly useful when constructing complex molecular architectures required for next-generation therapeutics targeting neurological, cardiovascular, and oncological indications.
- Superior Chemical Stability: The robust carbon-fluorine bonds ensure the molecule withstands harsh reaction conditions without degradation.
- High Reaction Efficiency: Optimized substitution patterns facilitate faster reaction kinetics and higher yields in downstream synthesis.
- Quality Assurance: Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity levels and impurity profiles.
- Scalable Supply: Our production facilities are equipped to handle both small-scale research requests and large-volume commercial orders.
Storage and Handling Guidelines
To maintain the integrity of 3-Bromo-2-Fluorobenzotrifluoride, proper storage protocols must be observed. The material should be kept in tightly sealed containers made of compatible materials to prevent moisture absorption or contamination. Storage areas must be cool, dry, and well-ventilated, away from direct sunlight and incompatible substances such as strong oxidizing agents. When handling this chemical, personnel should wear appropriate personal protective equipment, including chemical-resistant gloves and safety goggles, to ensure workplace safety.
We are committed to supporting our partners with technical expertise and logistical efficiency. Whether you require custom synthesis routes, detailed manufacturing process documentation, or competitive bulk pricing, our team is ready to assist. Contact us today to discuss your specific requirements and secure a reliable supply of this high-performance chemical intermediate for your production needs.
