Intermediates

3-Bromo-2-fluoropyridine

  • CAS No.36178-05-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 3-Bromo-2-fluoropyridine designed for pharmaceutical intermediate synthesis. Reliable supply with comprehensive quality documentation.

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Product Technical Details

Product Overview

3-Bromo-2-fluoropyridine is a highly valued heterocyclic building block extensively utilized in modern organic synthesis and medicinal chemistry. As a halogenated pyridine derivative, this compound features both bromine and fluorine substituents on the pyridine ring, offering unique reactivity profiles for various transformation reactions. Our manufacturing process ensures consistent quality and high purity levels, making it an ideal choice for research and industrial scale applications.

This chemical serves as a critical precursor in the development of complex pharmaceutical agents. The presence of the fluorine atom enhances metabolic stability in potential drug candidates, while the bromine functionality facilitates cross-coupling reactions such as Suzuki, Heck, or Buchwald-Hartwig aminations. We prioritize strict quality control measures to guarantee that every batch meets rigorous international standards for chemical intermediates.

Technical Specifications

ParameterValue
Chemical Name3-Bromo-2-fluoropyridine
CAS Number36178-05-9
Molecular FormulaC5H3BrFN
Molecular Weight175.99 g/mol
AppearanceYellow liquid
Purity≥98.0%
Density1.7±0.1 g/cm3
Boiling Point179.6±20.0 °C at 760 mmHg
Flash Point62.4±21.8 °C
Refractive Index1.534

Industrial Applications

The primary application of 3-Bromo-2-fluoropyridine lies within the pharmaceutical industry, where it acts as a key intermediate for synthesizing active pharmaceutical ingredients (APIs). Its structural properties allow chemists to introduce specific functional groups into complex molecular frameworks with high precision. Beyond pharmaceuticals, this compound is also applicable in agrochemical synthesis and materials science research.

  • Pharmaceutical intermediate synthesis for novel therapeutics
  • Cross-coupling reactions in organic chemistry
  • Development of fluorinated heterocyclic compounds
  • Agrochemical research and development
  • Custom synthesis projects requiring high purity building blocks

Quality Assurance And Storage

We understand that consistency is paramount in chemical manufacturing. Each production batch undergoes comprehensive analysis using advanced instrumentation including HPLC, GC, and NMR spectroscopy to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment to ensure full transparency and compliance with your internal quality standards.

Proper storage is essential to maintain the stability of 3-Bromo-2-fluoropyridine. The product should be kept in a tightly closed container within a cool, dry, and well-ventilated area. Protection from moisture and direct sunlight is recommended to prevent degradation. For large volume orders, we offer secure packaging in 25 KGS drums, ensuring safe global transportation. Our logistics team coordinates efficiently to deliver materials on time, supporting your production schedules without interruption.