Intermediates

3-Bromo-2-hydroxypyridine

  • CAS No.13466-43-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Bromo-2-hydroxypyridine (CAS 13466-43-8) is a essential beige solid intermediate for advanced organic synthesis and pharmaceutical manufacturing processes.

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Product Technical Details

Product Overview

3-Bromo-2-hydroxypyridine represents a critical halogenated heterocyclic compound within the realm of advanced organic chemistry. This specialized chemical serves as a fundamental building block for numerous complex synthesis pathways, particularly in the development of pharmaceutical agents and agrochemical formulations. Our manufacturing facility produces this compound using state-of-the-art bromination and hydrolysis techniques to ensure exceptional consistency and reliability for downstream applications.

As a key intermediate, this pyridine derivative offers superior reactivity profiles due to the strategic positioning of the bromine substituent relative to the hydroxyl group. This structural arrangement facilitates various nucleophilic substitution reactions and cross-coupling processes, making it an indispensable reagent for medicinal chemists and industrial process engineers alike. We prioritize strict quality control measures throughout production to maintain the integrity of the molecular structure.

Technical Specifications

Our commitment to quality is reflected in the rigorous testing protocols applied to every batch. The following table outlines the standard physical and chemical properties associated with our premium grade material. Customers can rely on these specifications for their process design and safety assessments.

ParameterSpecification
CAS Number13466-43-8
Molecular FormulaC5H4BrNO
Molecular Weight173.99 g/mol
AppearanceBeige solid
Purity (HPLC)≥99.0%
Melting Point185-189oC
Density1.776 g/cm3
Boiling Point336.6oC

Industrial Applications

The versatility of 3-Bromo-2-hydroxypyridine enables its use across multiple high-value sectors. Primarily, it functions as a precursor in the synthesis of biologically active molecules where the pyridine core is essential for target binding. The high purity level ensures minimal side reactions during scale-up, which is crucial for cost-effective manufacturing.

  • Pharmaceutical intermediate for novel drug discovery programs.
  • Agrochemical synthesis for developing next-generation crop protection agents.
  • Material science applications requiring functionalized heterocyclic structures.
  • Custom organic synthesis projects demanding precise halogenated building blocks.

Quality Assurance And Storage

We understand that stability and purity are paramount for chemical intermediates. Each production lot undergoes comprehensive analysis via High-Performance Liquid Chromatography (HPLC) to verify purity levels exceed 99.0%. Documentation including Certificates of Analysis (COA) is provided with every shipment to support regulatory compliance and quality audits.

Proper storage is essential to maintain product integrity over time. The material should be kept in a cool, ventilated environment away from direct sunlight and moisture sources. Standard packaging involves 25 kg drums, though we offer flexible packaging solutions tailored to specific customer logistics requirements. Our global supply chain ensures timely delivery while maintaining the highest safety standards during transportation.