3-Bromo-2-methoxyaniline
- CAS No.116557-46-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Bromo-2-methoxyaniline designed for pharmaceutical API synthesis. Ideal intermediate for Lacosamide production with strict quality control.
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Product Overview
3-Bromo-2-methoxyaniline is a specialized organic compound widely recognized for its critical role in the synthesis of advanced pharmaceutical active ingredients. As a key building block in medicinal chemistry, this brominated aniline derivative offers exceptional reactivity for nucleophilic substitution and coupling reactions. Our manufacturing process ensures consistent molecular integrity, making it a preferred choice for research laboratories and large-scale API production facilities globally. The compound is characterized by its stable aromatic structure and functional group compatibility, which facilitates efficient downstream processing.
Key Specifications
We adhere to rigorous enterprise standards to guarantee the reliability of every batch. The following table outlines the primary physical and chemical parameters verified through our quality control laboratories. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) to validate compliance with specified limits.
| Parameter | Specification |
|---|---|
| CAS Number | 116557-46-1 |
| Molecular Formula | C7H8BrNO |
| Molecular Weight | 202.048 g/mol |
| Appearance | Light yellow to brownish liquid |
| Assay (Purity) | ≥98.0% |
| Boiling Point | 267.9±20.0 °C at 760 mmHg |
| Density | 1.5±0.1 g/cm3 |
| Refractive Index | 1.596 |
Industrial Applications
The primary application of 3-Bromo-2-methoxyaniline lies in the pharmaceutical sector, specifically serving as a vital intermediate in the synthesis of Lacosamide. Lacosamide is a functionalized amino acid used in the management of partial-onset seizures, highlighting the importance of high-purity precursors in ensuring patient safety and drug efficacy. Beyond this specific pathway, the chemical structure allows for versatility in creating heterocyclic compounds and other complex organic molecules. Chemists utilize this intermediate for various coupling reactions, including palladium-catalyzed cross-couplings, due to the reactive bromine position ortho to the methoxy group. This positional arrangement provides unique steric and electronic properties beneficial for specific synthetic routes.
Quality Assurance and Storage
Quality is paramount in our production facility. We employ advanced analytical techniques such as HPLC and GC-MS to monitor impurity profiles, ensuring that related substances like 1-bromo-2-methoxy-3-nitrobenzene and 2-amino-6-bromophenol remain well below acceptable thresholds. Our commitment to excellence extends to packaging and logistics.
- Strict quality control protocols at every production stage.
- Impurity levels monitored to be less than 0.5% for individual known impurities.
- Packaged in 200 kg drums or customized containers based on client requirements.
- Storage recommended in a cool, ventilated area away from direct sunlight and moisture.
- Global shipping capabilities with secure handling procedures.
By choosing our 3-Bromo-2-methoxyaniline, partners gain access to a reliable supply chain backed by technical expertise and a dedication to regulatory compliance. We support our clients with detailed technical data sheets and responsive customer service to facilitate smooth integration into your manufacturing processes.
