3-Bromo-2-methoxypyridine
- CAS No.13472-59-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Bromo-2-methoxypyridine (CAS 13472-59-8), a versatile pyridine-based intermediate for advanced organic synthesis in pharmaceutical and agrochemical manufacturing.
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Product Overview
3-Bromo-2-methoxypyridine is a high-value halogenated heterocyclic compound widely employed as a key building block in modern organic synthesis. With its reactive bromine atom adjacent to an electron-donating methoxy group on the pyridine ring, this molecule offers exceptional regioselectivity for cross-coupling reactions such as Suzuki, Stille, and Negishi protocols. It serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs), crop protection agents, and functional materials.
Specifications
| Molecular Formula | C6H6BrNO |
|---|---|
| Molecular Weight | 188.02 g/mol |
| CAS Number | 13472-59-8 |
| Appearance | Colorless liquid |
| Purity | ≥99.0% |
| Density | 1.5856 g/cm³ |
| Boiling Point | 190.4°C |
| Flash Point | 93°C |
| Refractive Index | 1.566 |
Industrial Applications
As a specialized pyridine derivative, 3-Bromo-2-methoxypyridine is primarily utilized in the pharmaceutical and agrochemical sectors for constructing complex molecular architectures. Its structural features enable efficient functionalization at the C3 position, facilitating the introduction of aryl, alkyl, or heteroaryl moieties. This intermediate supports the scalable synthesis of drug candidates targeting neurological, oncological, and metabolic disorders, as well as next-generation herbicides and insecticides.
- Enables precise C–C and C–N bond formation via transition-metal catalysis
- Compatible with standard handling protocols for moisture-sensitive reagents
- Supplied in industrial-grade packaging with full analytical documentation (COA)
Stored in a cool, well-ventilated area away from ignition sources, this product maintains stability under recommended conditions and is available in 200 kg drums or custom packaging upon request.
