Intermediates

3-Bromo-4-chlorotoluene

  • CAS No.57310-39-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Bromo-4-chlorotoluene (CAS 57310-39-1), a versatile aromatic halogenated intermediate for advanced organic synthesis in pharmaceutical and agrochemical manufacturing.

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Product Technical Details

Product Overview

3-Bromo-4-chlorotoluene is a high-value aromatic halogenated compound widely employed as a key building block in complex organic synthesis. With the molecular formula C7H6BrCl and a molecular weight of 205.48 g/mol, this compound features both bromo and chloro substituents on a toluene backbone, offering orthogonal reactivity for selective cross-coupling and functionalization reactions. Its structural versatility makes it indispensable in the development of active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Specifications

Molecular FormulaC7H6BrCl
Molecular Weight205.480 g/mol
Density1.5 ± 0.1 g/cm³
Boiling Point229.1 ± 20.0 °C at 760 mmHg
Flash Point104.5 ± 11.9 °C
Vapour Pressure0.1 ± 0.4 mmHg at 25°C
Refractive Index1.566
AppearanceColorless transparent liquid
Assay≥98.0%

Industrial Applications

As a critical intermediate in fine chemical manufacturing, 3-Bromo-4-chlorotoluene serves multiple strategic roles:

  • Enables sequential palladium-catalyzed cross-coupling reactions due to differential reactivity of Br vs. Cl groups.
  • Acts as a precursor in the synthesis of heterocyclic scaffolds used in neurological therapeutics and advanced organic synthesis.
  • Facilitates the construction of complex molecular architectures in agrochemical R&D.
  • Supports material science applications requiring halogen-functionalized aromatics.

Stored in a cool, well-ventilated area away from ignition sources, this compound is typically supplied in 200 kg drums or customized packaging to meet global regulatory and logistical standards. Our stringent quality control ensures batch-to-batch consistency, full traceability, and compliance with international safety protocols.