3-Bromo-4-fluorobenzoic Acid
- CAS No.1007-16-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Bromo-4-fluorobenzoic Acid (CAS 1007-16-5) designed for advanced organic synthesis. Reliable supply with ≥99.0% purity for pharmaceutical and chemical manufacturing.
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Product Overview
3-Bromo-4-fluorobenzoic Acid is a highly specialized halogenated aromatic carboxylic acid utilized extensively in modern organic synthesis and pharmaceutical development. This compound features a benzoic acid backbone substituted with bromine and fluorine atoms at the third and fourth positions, respectively. This specific substitution pattern imparts unique reactivity profiles, making it an invaluable building block for constructing complex molecular architectures. Our manufacturing process ensures consistent quality and high purity levels suitable for demanding research and industrial applications.
As a key intermediate, this chemical serves as a critical precursor in the synthesis of various bioactive molecules. The presence of both bromine and fluorine functionalities allows for versatile chemical transformations, including cross-coupling reactions and nucleophilic substitutions. We prioritize strict quality control measures to guarantee that every batch meets the rigorous standards required by global pharmaceutical and fine chemical industries.
Key Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 3-Bromo-4-fluorobenzoic Acid |
| CAS Number | 1007-16-5 |
| Molecular Formula | C7H4BrFO2 |
| Molecular Weight | 219.01 g/mol |
| Appearance | Off-white to white powder |
| Purity (HPLC) | ≥99.0% |
| Melting Point | 138-140°C |
| Boiling Point | 306.6°C |
| Density | 1.789 g/cm³ |
Industrial Applications
This compound is primarily employed as an intermediate in the production of pharmaceuticals, agrochemicals, and advanced materials. Its structural properties facilitate its use in Suzuki-Miyaura coupling reactions, where the bromine atom acts as a leaving group for carbon-carbon bond formation. Additionally, the fluorine substituent enhances metabolic stability and lipophilicity in final drug candidates, making this acid a preferred choice for medicinal chemistry programs.
- Pharmaceutical Intermediate: Used in the synthesis of kinase inhibitors and other therapeutic agents.
- Agrochemical Synthesis: Serves as a building block for novel herbicides and pesticides.
- Material Science: Utilized in the development of organic electronic materials and polymers.
- Custom Synthesis: Available for tailored research projects requiring specific halogenated precursors.
Quality Assurance and Storage
We maintain a robust quality assurance system to ensure product integrity. Each batch undergoes comprehensive testing using High-Performance Liquid Chromatography (HPLC) to verify purity levels. Certificates of Analysis (COA) are provided with every shipment to confirm compliance with specified parameters. Proper handling and storage are essential to maintain the stability of this chemical.
Store the material in a cool, ventilated area away from direct sunlight and moisture. Containers should be kept tightly closed when not in use to prevent contamination or degradation. Personnel handling this substance should adhere to standard safety protocols, including the use of appropriate personal protective equipment such as gloves and safety goggles. Our logistics team ensures secure packaging, typically in 25 kg drums, with options for custom packaging based on specific customer requirements. We are committed to providing reliable global shipping solutions to support your production timelines.
