Intermediates

3-Bromo-4-fluorobenzonitrile

  • CAS No.79630-23-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Bromo-4-fluorobenzonitrile designed for advanced organic synthesis and pharmaceutical intermediate applications.

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Product Technical Details

Product Overview

3-Bromo-4-fluorobenzonitrile is a highly valued halogenated aromatic compound serving as a critical building block in modern organic synthesis. Characterized by the presence of both bromine and fluorine substituents on the benzene ring, this molecule offers unique reactivity profiles that are essential for constructing complex chemical architectures. Our facility specializes in the production of this fine chemical with stringent quality controls to ensure consistency across batches.

The strategic placement of the nitrile group alongside halogen atoms makes this compound an versatile precursor for cross-coupling reactions, nucleophilic substitutions, and heterocycle formations. It is widely utilized in the development of advanced materials, agrochemicals, and pharmaceutical intermediates where precise molecular engineering is required.

Technical Specifications

We adhere to rigorous manufacturing standards to deliver products that meet global industry requirements. The following table outlines the key physical and chemical properties of our standard grade material.

ParameterSpecification
Chemical Name3-Bromo-4-fluorobenzonitrile
CAS Number79630-23-2
Molecular FormulaC7H3BrFN
Molecular Weight200.008 g/mol
Purity (Assay)≥98.0%
AppearanceWhite powder
Melting Point54-58 °F (lit.)
Boiling Point229.1±20.0 °C at 760 mmHg
Density1.7±0.1 g/cm3

Industrial Applications

This fluorinated nitrile derivative is primarily employed as an intermediate in the synthesis of high-value organic compounds. In medicinal chemistry, the introduction of fluorine atoms can significantly enhance the metabolic stability and bioavailability of drug candidates. Consequently, this building block is frequently utilized in the research and development of novel therapeutic agents.

Beyond pharmaceuticals, 3-Bromo-4-fluorobenzonitrile finds application in the agrochemical sector for the production of pesticides and herbicides. The bromine atom facilitates palladium-catalyzed coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, allowing chemists to efficiently form carbon-carbon and carbon-heteroatom bonds. This versatility makes it a staple reagent in process chemistry and scale-up operations.

Quality Assurance and Logistics

Quality is paramount in our production process. Each batch undergoes comprehensive analysis using advanced spectroscopic methods to verify identity and purity. We provide a Certificate of Analysis (COA) with every shipment to ensure transparency and compliance with your internal quality standards.

Our packaging options are designed to maintain product integrity during transit. Standard packing includes 25 kg drums, though we offer flexible customization to meet specific client requirements. Storage recommendations include keeping the material in a cool, ventilated area away from incompatible substances. As a global manufacturer, we support international shipping and strive to deliver reliable supply chains for our partners worldwide.