3-Bromo-4-fluoronitrobenzene
- CAS No.701-45-1
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Bromo-4-fluoronitrobenzene (CAS 701-45-1), a versatile aromatic intermediate for advanced organic synthesis in pharmaceutical and agrochemical R&D.
Request Bulk PricingProduct Technical Details
Product Overview
3-Bromo-4-fluoronitrobenzene (CAS 701-45-1) is a high-value aromatic halogenated nitro compound widely employed as a key building block in complex organic synthesis. This yellow crystalline powder features a strategically positioned bromo, fluoro, and nitro group on the benzene ring, enabling selective cross-coupling, nucleophilic substitution, and reduction reactions. Its unique substitution pattern makes it indispensable in the development of active pharmaceutical ingredients (APIs), crop protection agents, and specialty functional materials.
Specifications
| Molecular Formula | C6H3BrFNO2 |
|---|---|
| Molecular Weight | 219.996 g/mol |
| Appearance | Yellow powder |
| Assay | ≥98.0% |
| Melting Point | 55°C |
| Boiling Point | 250.6±20.0°C at 760 mmHg |
| Density | 1.8±0.1 g/cm³ |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Refractive Index | 1.580 |
Industrial Applications
As a multifunctional electrophilic scaffold, 3-Bromo-4-fluoronitrobenzene serves critical roles across multiple high-tech sectors:
- Pharmaceutical intermediates: Enables Suzuki, Buchwald-Hartwig, and other Pd-catalyzed couplings to construct biaryl or aryl amine motifs found in modern therapeutics.
- Agrochemical synthesis: Used to generate fluorinated analogs with enhanced bioactivity and environmental stability.
- Materials science: Acts as a precursor for liquid crystals, OLED emitters, and high-performance polymers requiring precise electronic tuning.
Our product is manufactured under stringent quality control protocols, ensuring consistent batch-to-batch performance. Standard packaging is 25 kg per drum, with custom options available upon request. Store in a cool, dry, and well-ventilated area away from incompatible substances.
