Intermediates

3-Bromo-5-chloropyridin-2-amine

  • CAS No.26163-03-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade 3-Bromo-5-chloropyridin-2-amine for advanced organic synthesis. High purity assured with comprehensive COA and global shipping capabilities.

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Product Technical Details

Product Overview

3-Bromo-5-chloropyridin-2-amine represents a critical heterocyclic building block extensively utilized within the fine chemicals and pharmaceutical sectors. This halogenated aminopyridine derivative is characterized by its unique substitution pattern, featuring both bromine and chlorine atoms on the pyridine ring. Such structural attributes make it an exceptionally versatile precursor for complex organic synthesis pathways. Our manufacturing facility ensures that every batch meets rigorous international standards, providing researchers and industrial partners with a reliable source of high-performance chemical intermediates.

The compound is engineered to facilitate various cross-coupling reactions, including Suzuki and Buchwald-Hartwig aminations. The presence of distinct halogen sites allows for selective functionalization, enabling chemists to construct sophisticated molecular architectures with precision. The differential reactivity between the bromo and chloro substituents offers synthetic flexibility, allowing for stepwise modifications that are essential in multi-step synthesis routes. Whether used in the development of novel active pharmaceutical ingredients or advanced agrochemical formulations, this material serves as a foundational element for innovation in chemical science.

Technical Specifications

ParameterValue
Chemical Name3-Bromo-5-chloropyridin-2-amine
CAS Number26163-03-1
Molecular FormulaC5H4BrClN2
Molecular Weight207.46 g/mol
AppearanceWhite to light brown Crystalline powder
Assay≥98.0%
Moisture Content≤0.5%
Melting Point82-83°C
Boiling Point256.2°C
Density1.834 g/cm3

Industrial Applications

This specialized intermediate finds broad application across multiple high-value industries. Its primary utility lies in the synthesis of complex organic molecules where specific halogen placement is required for downstream reactivity. The high purity levels ensure minimal side reactions during critical synthesis stages. Key application areas include:

  • Pharmaceutical Intermediate Synthesis: Serving as a core structure for developing new therapeutic agents and drug candidates.
  • Agrochemical Development: Utilized in the creation of advanced crop protection chemicals and pesticides.
  • Material Science: Employed in the design of functionalized polymers and organic electronic materials.
  • Custom Organic Synthesis: Ideal for research laboratories requiring high purity reagents for method development and scale-up.

Quality Assurance and Storage

We maintain a strict quality control protocol to ensure consistency across all production lots. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) verifying purity and physical properties. To maintain stability, the product should be stored in a cool, ventilated environment away from direct sunlight and moisture. Proper handling procedures must be followed to ensure safety during industrial processing. Our commitment to quality ensures that 3-Bromo-5-chloropyridin-2-amine delivers consistent performance in your specific application requirements. Packaging options include 25 kg drums or customized solutions based on client logistics needs.