3-Bromo-5-fluoro-4-methoxyaniline
- CAS No.875664-44-1
- GradeIndustrial / Pharmaceutical
- Availabilityβ In Stock
High-purity 3-Bromo-5-fluoro-4-methoxyaniline designed for advanced pharmaceutical intermediate synthesis. Available in bulk quantities with comprehensive quality documentation.
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Product Overview
3-Bromo-5-fluoro-4-methoxyaniline represents a sophisticated halogenated aromatic amine essential for modern medicinal chemistry and organic synthesis. As a specialized fluorinated building block, this compound offers unique reactivity profiles due to the strategic positioning of bromine and fluorine substituents on the aniline core. Our manufacturing process ensures consistent quality suitable for demanding research and development pipelines as well as large-scale production environments.
The presence of the methoxy group enhances the electron density of the aromatic ring, while the halogen atoms provide versatile handles for cross-coupling reactions. This molecular architecture makes it an invaluable precursor for constructing complex pharmaceutical scaffolds, agrochemical agents, and advanced functional materials. We prioritize strict quality control measures to guarantee that every batch meets the rigorous standards required by global regulatory bodies.
Technical Specifications
Our production facility utilizes advanced analytical techniques to verify the identity and purity of this chemical intermediate. The following table outlines the key physical and chemical parameters that define our standard grade product. Customers can request customized specifications based on specific project requirements.
| Parameter | Specification |
|---|---|
| Chemical Name | 3-Bromo-5-fluoro-4-methoxyaniline |
| CAS Number | 875664-44-1 |
| Molecular Formula | C7H7BrFNO |
| Molecular Weight | 220.04 g/mol |
| Appearance | Light yellow solid |
| Purity | ≥98.0% |
| Density | 1.617 g/cm3 |
| Melting Point | 0-73°C |
| Boiling Point | 290.56°C at 760 mmHg |
| Flash Point | 129.53°C |
| Refractive Index | 1.573 |
Industrial Applications
This compound serves primarily as a critical intermediate in the synthesis of active pharmaceutical ingredients (APIs). The bromine atom facilitates palladium-catalyzed coupling reactions such as Suzuki-Miyaura or Buchwald-Hartwig aminations, enabling the formation of carbon-carbon and carbon-nitrogen bonds. Meanwhile, the fluorine substituent often improves the metabolic stability and bioavailability of the final drug molecule, a key consideration in modern drug design.
- Pharmaceutical Intermediate Synthesis
- Medicinal Chemistry Research
- Agrochemical Development
- Organic Material Science
- Custom Chemical Manufacturing
Beyond pharmaceuticals, this chemical finds utility in the development of specialized polymers and liquid crystals where precise electronic properties are required. Our team supports clients with technical data sheets and safety information to ensure seamless integration into your manufacturing processes.
Storage and Handling
To maintain optimal stability and safety, 3-Bromo-5-fluoro-4-methoxyaniline should be stored in a tightly closed container within a cool, dry, and well-ventilated area. It is crucial to keep the material away from incompatible substances such as strong oxidizing agents and acids. Standard personal protective equipment including gloves and safety goggles should be worn during handling to prevent skin contact or inhalation.
We offer flexible packaging options including 25kg drums to accommodate various supply chain needs. All shipments are accompanied by a Certificate of Analysis (COA) verifying batch-specific quality metrics. For bulk orders or technical inquiries regarding synthesis routes, our global sales team is ready to provide competitive pricing and logistical support.
