3-Bromo-5-fluoroanisole
- CAS No.29578-39-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Bromo-5-Fluoroanisole (CAS 29578-39-0) designed for advanced organic synthesis and pharmaceutical intermediate applications.
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Product Overview
3-Bromo-5-fluoroanisole is a specialized halogenated aromatic ether compound that serves as a critical building block in modern organic synthesis. Characterized by its unique substitution pattern featuring both bromine and fluorine atoms on the benzene ring, this chemical intermediate offers exceptional reactivity for cross-coupling reactions and nucleophilic substitutions. Our facility produces this compound under strict quality control standards to ensure consistency for research and industrial-scale manufacturing processes.
As a versatile precursor, this material is extensively utilized in the development of pharmaceutical agents, agrochemical formulations, and advanced functional materials. The presence of the methoxy group alongside halogen substituents provides chemists with multiple handles for further functionalization, making it an invaluable asset in multi-step synthesis routes.
Technical Specifications
We maintain rigorous testing protocols to guarantee the purity and physical properties of every batch. The following table outlines the key parameters verified through our quality assurance laboratory using advanced analytical techniques such as GC and HPLC.
| Parameter | Specification |
|---|---|
| CAS Number | 29578-39-0 |
| Molecular Formula | C7H6BrFO |
| Molecular Weight | 205.024 g/mol |
| Appearance | Colorless transparent liquid |
| Assay (Purity) | ≥98.0% |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 186.6±20.0 °C at 760 mmHg |
| Flash Point | 79.3±6.0 °C |
| Refractive Index | 1.519 |
Industrial Applications
The primary utility of 3-Bromo-5-fluoroanisole lies in its role as a key intermediate for complex molecule construction. In the pharmaceutical sector, it is employed in the synthesis of various therapeutic candidates where specific halogen positioning is required for biological activity optimization. The fluorine atom enhances metabolic stability, while the bromine site facilitates palladium-catalyzed coupling reactions.
- Pharmaceutical Intermediate: Used in the development of novel drug substances requiring substituted anisole scaffolds.
- Agrochemical Synthesis: Serves as a precursor for herbicides and pesticides requiring specific aromatic substitution patterns.
- Material Science: Utilized in the creation of organic electronic materials and liquid crystal compounds.
- Research and Development: Essential reagent for academic and industrial laboratories focusing on organic methodology.
Quality Assurance and Packaging
Every shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing batch-specific test results. We understand the importance of supply chain reliability for continuous manufacturing operations. Our production capacity allows us to fulfill bulk orders consistently while maintaining the high purity levels required for sensitive synthetic applications.
Standard packaging consists of 200 kg drums, ensuring safe transport and storage. However, we offer flexible packaging solutions tailored to specific customer requirements, including smaller quantities for research purposes. All containers are labeled according to global hazardous material transport regulations.
Storage and Handling
To maintain product integrity, 3-Bromo-5-fluoroanisole should be stored in a cool, ventilated area away from direct sunlight and heat sources. Containers must remain tightly closed when not in use to prevent moisture absorption or contamination. Personnel handling this chemical should adhere to standard safety protocols, including the use of appropriate personal protective equipment such as gloves and safety goggles. A detailed Material Safety Data Sheet (MSDS) is available upon request to ensure safe handling practices within your facility.
