3-Bromo-5-fluoropyridine
- CAS No.407-20-5
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Bromo-5-fluoropyridine (CAS 407-20-5) designed for advanced pharmaceutical synthesis. Reliable supply with strict quality control for global research and production needs.
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Product Overview
3-Bromo-5-fluoropyridine is a highly valued heterocyclic compound extensively utilized in the field of medicinal chemistry and organic synthesis. As a halogenated pyridine derivative, it serves as a versatile building block for the construction of complex molecular architectures. Our facility specializes in the production of this chemical intermediate with a commitment to exceeding industry standards for purity and consistency. The compound is characterized by its distinct reactivity profile, making it an essential reagent for cross-coupling reactions and nucleophilic substitutions in the development of novel therapeutic agents.
We understand the critical nature of supply chain reliability in the pharmaceutical sector. Therefore, our manufacturing processes are optimized to ensure batch-to-batch reproducibility. Each production run undergoes rigorous analytical testing to confirm identity and purity levels. This dedication to quality makes our 3-Bromo-5-fluoropyridine a preferred choice for research laboratories and large-scale production facilities alike.
Key Specifications
To guarantee performance in sensitive synthetic pathways, we maintain strict control over physical and chemical parameters. The following table outlines the standard specifications for our commercial grade product. Custom specifications may be available upon request for specific project requirements.
| Parameter | Specification |
|---|---|
| CAS Number | 407-20-5 |
| Molecular Formula | C5H3BrFN |
| Molecular Weight | 175.99 g/mol |
| Appearance | Colorless liquid |
| Purity | ≥98.0% |
| Density | 1.7±0.1 g/cm3 |
| Boiling Point | 152.5±20.0 °C at 760 mmHg |
| Melting Point | 24-28 °C |
| Flash Point | 46.0±21.8 °C |
| Refractive Index | 1.534 |
Industrial Applications
The primary application of 3-Bromo-5-fluoropyridine lies in the synthesis of pharmaceutical intermediates. Its dual halogen substitution pattern allows for selective functionalization, enabling chemists to introduce diverse functional groups at specific positions on the pyridine ring. This capability is crucial in the structure-activity relationship (SAR) studies during drug discovery processes. Additionally, this compound finds utility in the development of agrochemicals and advanced materials where fluorinated heterocycles are required to enhance metabolic stability or modify electronic properties.
Our clients leverage this chemical for various transformation reactions including Suzuki-Miyaura coupling, Buchwald-Hartwig amination, and lithiation followed by electrophilic quenching. The high purity ensures minimal side reactions, leading to improved yields and simplified downstream purification processes.
Quality Assurance and Safety
Quality is the cornerstone of our operation. Every batch of 3-Bromo-5-fluoropyridine is accompanied by a comprehensive Certificate of Analysis (COA). Our quality control laboratory employs advanced instrumentation such as HPLC, GC-MS, and NMR to verify composition. We adhere to international safety guidelines for the handling of chemical substances. Proper personal protective equipment (PPE) should be worn during handling, and operations should be conducted in a well-ventilated area or fume hood.
For storage, the product must be kept in a tightly closed container to prevent moisture absorption and contamination. It should be stored in a cool, dry place away from incompatible materials such as strong oxidizing agents. We offer flexible packaging options including 25 kg drums to suit various logistical needs. Our global distribution network ensures timely delivery to support your production schedules without interruption.
