3-Bromo-5-iodopyridine
- CAS No.233770-01-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Bromo-5-iodopyridine (CAS 233770-01-9), a versatile halogenated pyridine building block for advanced organic synthesis and pharmaceutical intermediates.
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Product Overview
3-Bromo-5-iodopyridine is a highly valuable dihalogenated heterocyclic compound widely employed as a key intermediate in modern organic synthesis. Its dual halogen functionality—featuring both bromine and iodine substituents at the 3- and 5-positions of the pyridine ring—enables sequential and orthogonal cross-coupling reactions, making it indispensable in the construction of complex molecular architectures for agrochemicals, pharmaceuticals, and functional materials.
Specifications
| Molecular Formula | C5H3BrIN |
|---|---|
| Molecular Weight | 283.89 g/mol |
| Appearance | Yellow to brown solid |
| Assay | ≥98.0% |
| Moisture | ≤0.5% |
| Melting Point | 131.3–131.4°C |
| Boiling Point | 266.5°C |
| Density | 2.347 g/cm³ |
| Flash Point | 115°C |
| Refractive Index | 1.665 |
Industrial Applications
This compound serves primarily as a specialty intermediate in multi-step synthetic pathways. Its regioselective reactivity allows chemists to leverage palladium-catalyzed couplings such as Suzuki, Sonogashira, and Buchwald-Hartwig aminations with high precision. Common applications include:
- Synthesis of kinase inhibitors and other targeted therapeutics
- Construction of ligands for catalytic systems
- Development of novel electronic and optoelectronic materials
- Preparation of bioactive molecules in medicinal chemistry research
Stored in a cool, well-ventilated area away from light and moisture, 3-Bromo-5-iodopyridine maintains stability under recommended conditions. Standard packaging is 25 kg per drum, with custom options available to meet specific industrial or laboratory requirements.
