Intermediates

3-Bromo-5-methylpicolinonitrile

  • CAS No.474824-78-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade 3-Bromo-5-methylpicolinonitrile designed for complex organic synthesis pathways. High purity assurance with global logistics support.

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Product Technical Details

Product Overview

3-Bromo-5-methylpicolinonitrile is a highly specialized heterocyclic compound that serves as a fundamental building block in modern organic chemistry. Characterized by its unique pyridine ring structure substituted with both bromine and nitrile functional groups, this chemical offers exceptional versatility for synthetic transformations. Our facility produces this compound under strict quality control protocols to ensure consistent performance in downstream applications. The strategic positioning of the bromine atom at the third position facilitates various cross-coupling reactions, making it an indispensable reagent for research and development teams working on advanced molecular architectures.

Key Specifications

ParameterValue
Chemical Name3-Bromo-5-methylpicolinonitrile
CAS Number474824-78-7
Molecular FormulaC7H5BrN2
Molecular Weight197.03 g/mol
Purity (Assay)≥98.0%
AppearanceWhite solid

Industrial Applications

This brominated pyridine derivative is primarily utilized as a critical intermediate in the synthesis of complex pharmaceutical agents and agrochemical products. The nitrile group provides a handle for further functionalization, such as hydrolysis to carboxylic acids or reduction to amines, while the bromine moiety enables palladium-catalyzed coupling reactions like Suzuki-Miyaura or Buchwald-Hartwig processes. Researchers value this material for its stability and reactivity profile, which allows for efficient scale-up from laboratory benchtop to pilot plant operations. It is particularly suitable for projects requiring high regioselectivity and minimal impurity profiles in the final active ingredients.

Quality Assurance and Storage

  • Each batch undergoes rigorous analytical testing including HPLC and NMR to verify structural integrity and purity levels.
  • We provide comprehensive Certificates of Analysis (COA) with every shipment to ensure full traceability and compliance.
  • Products are packaged in secure 25 kg drums or customized containers based on specific client logistical requirements.
  • Storage recommendations include keeping the material in a cool, ventilated area away from direct sunlight and moisture to maintain stability.
  • Our global supply chain ensures timely delivery while adhering to all international shipping regulations for chemical substances.