3-Bromo-5-(trifluoromethyl)pyridine
- CAS No.436799-33-6
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-quality 3-Bromo-5-(trifluoromethyl)pyridine (CAS 436799-33-6) for pharmaceutical synthesis. High purity ≥98% available in bulk quantities with full documentation.
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Product Overview
3-Bromo-5-(trifluoromethyl)pyridine is a highly specialized fluorinated heterocyclic compound that serves as a critical building block in modern organic synthesis. This pyridine derivative combines the reactivity of a bromine substituent with the metabolic stability and lipophilicity provided by the trifluoromethyl group. Such structural features make it an invaluable asset for medicinal chemists and process researchers aiming to develop novel therapeutic agents.
Our manufacturing facility ensures that every batch of this chemical intermediate meets rigorous international standards. The compound is designed to facilitate cross-coupling reactions, nucleophilic substitutions, and other transformative processes essential for constructing complex molecular architectures. By integrating this material into your supply chain, you gain access to a reliable source of high-performance chemical raw materials.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 3-Bromo-5-(trifluoromethyl)pyridine |
| CAS Number | 436799-33-6 |
| Molecular Formula | C6H3BrF3N |
| Molecular Weight | 225.99 g/mol |
| Appearance | White Crystalline Powder |
| Purity | ≥98.0% |
| Melting Point | 44-46 °C |
| Boiling Point | 166.0±35.0 °C at 760 mmHg |
| Density | 1.7±0.1 g/cm3 |
| Flash Point | 54.2±25.9 °C |
| Refractive Index | 1.471 |
Key Features and Advantages
- High Chemical Purity: Guaranteed minimum purity of 98.0% to ensure consistent reaction outcomes.
- Enhanced Reactivity: The bromine position allows for versatile palladium-catalyzed coupling reactions.
- Metabolic Stability: The trifluoromethyl moiety improves the pharmacokinetic profile of downstream products.
- Strict Quality Control: Every lot undergoes comprehensive analysis including HPLC, NMR, and GC-MS.
- Scalable Supply: Capable of fulfilling both laboratory-scale research needs and large-scale industrial production.
Industrial Applications
This compound is primarily utilized as a key intermediate in the pharmaceutical industry. It acts as a precursor for the synthesis of various active pharmaceutical ingredients (APIs) where fluorinated pyridine structures are required. The unique electronic properties of the molecule enable chemists to introduce specific functional groups with high precision.
Beyond pharmaceuticals, this chemical finds applications in agrochemical research and advanced material science. Its stability under various conditions makes it suitable for developing crop protection agents and specialized organic materials. Researchers value this building block for its ability to streamline synthesis routes and reduce overall production costs.
Quality Assurance and Packaging
We adhere to strict quality management systems to maintain product integrity. Each shipment is accompanied by a Certificate of Analysis (COA) detailing all relevant physical and chemical properties. Our packaging ensures protection against moisture and contamination during transit.
Standard packaging includes 25 kg drums, customized according to client requirements. Storage recommendations include keeping the container tightly closed in a cool, dry, and well-ventilated area. Our logistics team supports global shipping, ensuring timely delivery while complying with all international chemical transport regulations. For specific technical data or bulk pricing inquiries, our sales team is ready to assist.
