Intermediates

3-Bromo-6-chloro-2-fluoropyridine

  • CAS No.885952-18-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Bromo-6-chloro-2-fluoropyridine (CAS 885952-18-1) designed for pharmaceutical synthesis. Reliable supply with strict quality control for global research and production needs.

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Product Technical Details

Product Overview

3-Bromo-6-chloro-2-fluoropyridine is a highly specialized halogenated heterocyclic compound serving as a critical building block in modern medicinal chemistry. This multifunctional pyridine derivative features distinct reactive sites at the 2, 3, and 6 positions, enabling versatile synthetic transformations. Our manufacturing process ensures exceptional batch-to-batch consistency, making it an ideal candidate for complex organic synthesis and drug discovery programs.

The strategic placement of bromine, chlorine, and fluorine atoms allows chemists to perform selective cross-coupling reactions, nucleophilic substitutions, and lithiation processes. This flexibility is essential for constructing advanced pharmaceutical APIs, agrochemical agents, and functional materials. We adhere to rigorous production standards to deliver material that meets the demanding requirements of global research laboratories and industrial scale-up operations.

Technical Specifications

ParameterValue
Chemical Name3-Bromo-6-chloro-2-fluoropyridine
CAS Number885952-18-1
Molecular FormulaC5H2BrClFN
Molecular Weight210.43 g/mol
Purity≥99.0%
AppearanceWhite Crystalline Powder
Boiling Point212.0±35.0 °C at 760 mmHg
Density1.8±0.1 g/cm3

Industrial Applications

This compound is primarily utilized as a key intermediate in the synthesis of pharmaceutical ingredients. The presence of multiple halogen substituents facilitates diverse chemical modifications, supporting the development of kinase inhibitors, antiviral agents, and other therapeutic classes. Researchers value this building block for its stability and reactivity profile, which streamlines the pathway from lead optimization to clinical candidate selection.

Beyond pharmaceuticals, 3-Bromo-6-chloro-2-fluoropyridine finds applications in the agrochemical sector for creating novel pesticides and herbicides. Its robust chemical structure also supports materials science initiatives where fluorinated pyridines are required for specific electronic or optical properties. Our supply chain is optimized to support both small-scale research quantities and large-scale commercial production runs.

Quality Assurance and Storage

Quality is paramount in our manufacturing workflow. Each batch undergoes comprehensive analytical testing using HPLC, NMR, and GC-MS to verify identity and purity levels. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure full transparency and compliance with your internal quality standards. Our facility operates under strict environmental and safety protocols to guarantee product integrity.

For optimal stability, store this material in a tightly closed container within a cool, dry environment. Protect from moisture and direct sunlight to maintain chemical properties over extended periods. Proper handling procedures should be followed according to standard laboratory safety guidelines. Contact our technical sales team for detailed safety data sheets and customized packaging solutions tailored to your specific logistical requirements.