Intermediates

3-Bromo-6-hydroxy-2-methylpyridine

  • CAS No.54923-31-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Bromo-6-hydroxy-2-methylpyridine (CAS 54923-31-8) designed for advanced organic synthesis. Reliable supply with strict quality control for pharmaceutical intermediates.

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Product Technical Details

Product Overview

3-Bromo-6-hydroxy-2-methylpyridine is a specialized heterocyclic compound characterized by its unique pyridine ring structure substituted with bromo, hydroxy, and methyl functional groups. This chemical serves as a critical building block in the realm of advanced organic synthesis, particularly within the pharmaceutical and agrochemical industries. Its specific substitution pattern allows for versatile reactivity, making it an invaluable precursor for constructing more complex molecular architectures. Our facility ensures that every batch meets rigorous international standards for purity and consistency, supporting researchers and manufacturers in achieving reliable outcomes in their synthesis pathways.

The compound is meticulously produced using state-of-the-art manufacturing processes that prioritize both yield and quality. As a key intermediate, it facilitates various coupling reactions and functional group transformations. The presence of the bromine atom offers a handle for cross-coupling reactions, while the hydroxy and methyl groups provide additional sites for chemical modification. This versatility makes it a preferred choice for process chemistry teams looking to optimize their synthetic routes for active pharmaceutical ingredients and other high-value chemicals.

Technical Specifications

We maintain strict quality control protocols to ensure that the physical and chemical properties of 3-Bromo-6-hydroxy-2-methylpyridine remain consistent across all production lots. The following table outlines the key specifications that define the quality of our product. Each parameter is tested using validated analytical methods to guarantee compliance with the stated requirements.

ParameterSpecification
Chemical Name3-Bromo-6-hydroxy-2-methylpyridine
CAS Number54923-31-8
Molecular FormulaC6H6BrNO
Molecular Weight188.022 g/mol
AppearanceLight yellow crystal
Assay (Purity)≥98.0%
Melting Point199-203 °C (lit.)
Boiling Point314.9 ± 37.0 °C at 760 mmHg
Density1.7 ± 0.1 g/cm3
Flash Point144.2 ± 26.5 °C

Industrial Applications

Due to its robust chemical structure and high reactivity, this pyridine derivative finds extensive application in multiple sectors. It is primarily utilized as a fundamental intermediate in the synthesis of various therapeutic agents. The compound's stability under standard processing conditions allows it to be integrated into complex multistep syntheses without compromising the integrity of the final product. Additionally, it is employed in the development of novel agrochemicals where specific heterocyclic motifs are required for biological activity.

  • Pharmaceutical Intermediate: Used in the synthesis of kinase inhibitors and other targeted therapies.
  • Heterocyclic Chemistry: Serves as a core structure for building diverse pyridine-based libraries.
  • Research and Development: Essential for academic and industrial labs exploring new synthetic methodologies.
  • Custom Synthesis: Available for tailored production runs to meet specific project requirements.

Quality Assurance and Storage

Quality is the cornerstone of our manufacturing philosophy. Every drum of 3-Bromo-6-hydroxy-2-methylpyridine is accompanied by a comprehensive Certificate of Analysis (COA) that details the results of all quality control tests. Our packaging ensures that the product remains protected from environmental factors during transit. The standard packaging configuration is 25 kg per drum, though we offer flexible packaging solutions to accommodate specific customer logistics and handling needs.

Proper storage is essential to maintain the longevity and efficacy of the chemical. We recommend storing the material in a cool, ventilated place away from direct sunlight and sources of ignition. The container should be kept tightly closed when not in use to prevent moisture absorption and contamination. Our global supply chain network ensures timely delivery to clients worldwide, supported by our dedicated technical team who are available to provide guidance on handling and application. Contact us today for bulk pricing and to discuss how our high-quality intermediates can support your production goals.