Intermediates

3-Bromobenzotrifluoride

  • CAS No.401-78-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

3-Bromobenzotrifluoride is a high-purity pharmaceutical intermediate used in organic synthesis. Available in bulk with strict quality control.

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Product Technical Details

Product Overview

3-Bromobenzotrifluoride is a specialized fluorinated aromatic compound widely recognized for its stability and reactivity in advanced organic synthesis. As a critical building block, this chemical serves as a foundational element in the manufacturing of various pharmaceutical agents and agrochemical products. Our facility produces this intermediate under stringent quality management systems to ensure consistent molecular integrity and performance across diverse industrial applications.

The compound features a benzene ring substituted with both bromine and trifluoromethyl groups at the meta position. This specific structural arrangement enhances its utility in cross-coupling reactions and nucleophilic substitutions. Manufacturers rely on this material for its reliable boiling point and density characteristics, which facilitate precise handling during large-scale production processes.

Key Specifications

We maintain rigorous standards for physical and chemical properties to meet global industry requirements. The following table outlines the typical specifications verified through our internal quality control laboratories. Each batch undergoes comprehensive testing to confirm compliance with stated parameters.

Items of AnalysisStandard of AnalysisTest Results
AppearanceLight yellow liquidConform
Assay≥98.0%99.12%
Boiling point151-152℃152℃
Moisture≤0.1%0.05%
ConclusionConforms to Factory Standard

Quality Assurance

Quality is the cornerstone of our manufacturing philosophy. Every drum of 3-Bromobenzotrifluoride is accompanied by a Certificate of Analysis (COA) detailing specific batch data. Our analytical methods include gas chromatography and refractive index testing to verify purity levels exceeding 99 percent. This commitment to transparency ensures that downstream processors can maintain their own quality certifications without interruption.

We employ state-of-the-art storage facilities to prevent degradation prior to shipment. Containers are sealed tightly to protect against moisture absorption and contamination. Our logistics team coordinates global shipping to ensure timely delivery while maintaining product integrity throughout the transit process.

Industrial Applications

This fluorinated intermediate is primarily utilized in the synthesis of complex pharmaceutical molecules. The presence of the trifluoromethyl group often enhances the metabolic stability and lipophilicity of final drug candidates. Chemists value this reagent for its compatibility with palladium-catalyzed coupling reactions, which are essential in modern medicinal chemistry workflows.

Beyond pharmaceuticals, this compound finds application in the development of advanced materials and agrochemical formulations. Its chemical stability allows it to withstand harsh reaction conditions, making it a versatile tool for research and development teams aiming to innovate new molecular structures.

Storage and Handling

Proper storage is essential to maintain the chemical properties of 3-Bromobenzotrifluoride. Containers should be kept in a cool, dry environment away from direct sunlight and heat sources. Personnel handling this material must adhere to standard safety protocols, including the use of appropriate personal protective equipment such as gloves and safety goggles.

In case of spills, standard chemical containment procedures should be followed immediately. Ventilation systems must be operational in storage areas to prevent vapor accumulation. By following these guidelines, facilities can ensure a safe working environment while maximizing the shelf life and performance of this valuable chemical intermediate.