Intermediates

3-Chloro-2-fluorobenzoic acid

  • CAS No.161957-55-7
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Chloro-2-fluorobenzoic acid designed for advanced organic synthesis. Reliable supply with ≥99.0% assay and comprehensive quality documentation.

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Product Technical Details

Product Overview

3-Chloro-2-fluorobenzoic acid is a highly valued halogenated aromatic compound serving as a critical building block in modern organic synthesis. This fluorinated benzoic acid derivative combines both chloro and fluoro substituents on the benzene ring, offering unique reactivity profiles for complex molecular construction. Our facility produces this intermediate under strict quality control standards to ensure consistent performance in downstream chemical processes.

The compound is characterized by its stability and versatile functional groups, making it an essential precursor for pharmaceutical research, agrochemical development, and advanced material science. We specialize in supplying bulk quantities to industrial partners who require reliable raw materials for large-scale production runs.

Technical Specifications

ParameterValue
Chemical Name3-Chloro-2-fluorobenzoic acid
CAS Number161957-55-7
Molecular FormulaC7H4ClFO2
Molecular Weight174.56 g/mol
AppearanceWhite to light yellow crystalline powder
Assay≥99.0%
Moisture Content≤0.2%
Melting Point177-180°C
Density1.789 g/cm3

Industrial Applications

This fluorinated intermediate finds extensive use in the synthesis of biologically active molecules. In the pharmaceutical sector, it serves as a key starting material for developing kinase inhibitors and other therapeutic agents targeting specific enzymatic pathways. The presence of the fluorine atom often enhances metabolic stability and bioavailability in final drug candidates.

Beyond pharmaceuticals, 3-Chloro-2-fluorobenzoic acid is utilized in agrochemical formulations where halogenated structures provide necessary pesticidal or herbicidal activity. Material scientists also leverage this compound for creating specialized polymers and liquid crystals where precise electronic properties are required. Our manufacturing process ensures low impurity levels, which is crucial for sensitive catalytic reactions.

Quality Assurance And Safety

Every batch undergoes rigorous analytical testing including HPLC, NMR, and moisture analysis to verify compliance with specified parameters. We provide a comprehensive Certificate of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production facility adheres to international safety standards for handling halogenated organic compounds.

Proper handling procedures should be followed to minimize exposure. The product should be used in a well-ventilated environment with appropriate personal protective equipment. We recommend consulting the Safety Data Sheet (SDS) for detailed hazard information and emergency measures before processing.

Packaging And Storage

Standard packaging consists of 25 kg drums lined with protective inner bags to prevent moisture absorption and contamination. Custom packaging solutions are available upon request to meet specific logistical requirements. The product should be stored in a cool, dry, and ventilated area away from direct sunlight and incompatible materials.

Proper sealing after each use is essential to maintain product integrity over time. Our logistics team ensures secure transportation with full documentation for global delivery. Contact our sales team for current bulk pricing and lead time information tailored to your project needs.