3-Chloro-2-iodopyridine
- CAS No.77332-89-9
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Chloro-2-iodopyridine (CAS 77332-89-9) designed for advanced organic synthesis. Reliable supply for pharmaceutical and agrochemical research.
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Product Overview
3-Chloro-2-iodopyridine is a highly specialized halogenated heterocyclic compound that serves as a critical building block in modern organic synthesis. As a dual-functionalized pyridine derivative, this molecule offers unique reactivity profiles due to the presence of both chloro and iodo substituents on the pyridine ring. This structural arrangement allows chemists to perform selective cross-coupling reactions, making it an invaluable asset in the development of complex pharmaceutical agents and advanced agrochemical formulations.
Our manufacturing process ensures that every batch meets stringent quality standards suitable for research and industrial scale-up. The compound is characterized by its stability and high reactivity under standard palladium-catalyzed conditions, facilitating efficient carbon-carbon and carbon-heteroatom bond formations. We prioritize consistency and purity to support our partners in achieving reliable synthetic outcomes.
Technical Specifications
The following table outlines the key physical and chemical properties of our premium grade 3-Chloro-2-iodopyridine. These parameters are verified through rigorous analytical testing including HPLC, NMR, and mass spectrometry to guarantee compliance with international standards.
| Parameter | Value |
|---|---|
| CAS Number | 77332-89-9 |
| Molecular Formula | C5H3ClIN |
| Molecular Weight | 239.441 g/mol |
| Appearance | Gray-white crystal |
| Assay (Purity) | ≥98.0% |
| Density | 2.1±0.1 g/cm3 |
| Boiling Point | 245.0±20.0 °C at 760 mmHg |
| Flash Point | 102.0±21.8 °C |
Industrial Applications
This intermediate is extensively utilized in the pharmaceutical industry for the synthesis of kinase inhibitors and other therapeutic small molecules. The differential reactivity between the iodine and chlorine atoms allows for sequential functionalization, enabling the construction of sophisticated molecular architectures required in drug discovery pipelines. Additionally, it finds application in the agrochemical sector for developing novel pesticides and herbicides with improved environmental profiles.
Material science researchers also leverage this compound for creating functionalized polymers and organic electronic materials. Its robustness under various reaction conditions makes it a preferred choice for Suzuki, Stille, and Negishi coupling reactions. Our team provides technical support to help optimize these synthetic routes for maximum yield and efficiency.
Quality Assurance and Packaging
We maintain a comprehensive quality management system to ensure product integrity from synthesis to delivery. Each shipment is accompanied by a Certificate of Analysis (COA) detailing batch-specific test results. Our standard packaging consists of 25 kg drums, which are designed to protect the material from moisture and light during transit. Custom packaging solutions are available upon request to accommodate specific logistical requirements or smaller research quantities.
Storage and Safety
To maintain optimal stability, 3-Chloro-2-iodopyridine should be stored in a cool, ventilated place away from direct sunlight and sources of ignition. The container must remain tightly closed when not in use to prevent exposure to atmospheric moisture. Handling should be conducted in accordance with standard laboratory safety protocols, including the use of appropriate personal protective equipment. We are committed to supplying safe and compliant chemical solutions to our global clientele.
