3-Chloro-2-(trifluoromethyl)aniline
- CAS No.432-21-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Chloro-2-(trifluoromethyl)aniline liquid designed for advanced pharmaceutical intermediate synthesis and organic chemistry applications.
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Product Overview
3-Chloro-2-(trifluoromethyl)aniline represents a critical fluorinated building block within the realm of modern organic synthesis. As a specialized aromatic amine derivative, this compound features a unique structural arrangement where a chloro group and a trifluoromethyl group are positioned on the benzene ring relative to the amino functionality. This specific substitution pattern imparts distinct electronic and steric properties, making it an invaluable precursor for the construction of complex molecular architectures.
Our manufacturing process ensures that every batch meets rigorous international standards for chemical purity and consistency. The presence of the trifluoromethyl group enhances metabolic stability and lipophilicity in downstream products, which is particularly desirable in medicinal chemistry and agrochemical development. We supply this material as a clear liquid, ready for immediate integration into various synthetic routes without extensive preliminary purification.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 432-21-3 |
| Molecular Formula | C7H5ClF3N |
| Molecular Weight | 195.57 g/mol |
| Appearance | Colorless to Pale Yellow Liquid |
| Purity | ≥99.0% |
| Density | 1.425 g/cm3 |
| Boiling Point | 238.2°C at 760 mmHg |
| Flash Point | 97.9°C |
| Refractive Index | 1.5 |
Industrial Applications
This fluorinated aniline derivative serves primarily as a versatile intermediate in the pharmaceutical and fine chemical industries. Its reactivity profile allows it to participate in a wide array of transformation reactions, including nucleophilic substitutions, cross-coupling reactions, and heterocycle formations. Chemists utilize this building block to introduce specific fluorinated motifs into lead compounds, optimizing their biological activity and pharmacokinetic properties.
- Pharmaceutical Intermediate Synthesis: Used extensively in the preparation of novel therapeutic agents requiring fluorinated aromatic cores.
- Agrochemical Development: Acts as a key precursor for herbicides and pesticides where enhanced environmental stability is required.
- Material Science: Employed in the synthesis of specialized polymers and liquid crystals with unique thermal and optical characteristics.
- Custom Organic Synthesis: Suitable for research and development projects focusing on structure-activity relationship studies.
Quality Assurance and Storage
Quality control is paramount in our production facility. Each drum of 3-Chloro-2-(trifluoromethyl)aniline undergoes comprehensive testing using advanced analytical techniques such as GC-MS and HPLC to verify identity and purity levels. We provide a Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your internal quality standards.
For optimal stability, this product should be stored in tightly closed containers at room temperature, away from direct sunlight and moisture. Proper handling procedures include the use of personal protective equipment (PPE) such as gloves and safety goggles, as well as working in a well-ventilated area to minimize exposure to vapors. Our global logistics network ensures timely delivery while maintaining the integrity of the chemical throughout the supply chain.
