3-Chloro-4-fluoro-5-(trifluoromethyl)aniline

Product Overview

3-Chloro-4-fluoro-5-(trifluoromethyl)aniline is a highly specialized fluorinated building block designed for advanced organic synthesis applications. As a key intermediate, this compound plays a critical role in the development of novel pharmaceutical agents and agrochemical formulations. The unique substitution pattern, featuring chloro, fluoro, and trifluoromethyl groups on the aniline ring, provides exceptional reactivity and stability for downstream chemical transformations. Our manufacturing process ensures consistent quality and high purity levels suitable for rigorous research and industrial production scales.

In the modern chemical industry, fluorinated intermediates are increasingly valued for their ability to enhance the metabolic stability and bioavailability of final products. This specific aniline derivative offers versatile coupling opportunities, making it an essential component for medicinal chemists and process development teams. We maintain strict quality control protocols to guarantee that every batch meets international standards for purity and performance.

Technical Specifications

Physical and Chemical Properties

This compound exhibits robust physical properties that facilitate safe handling and processing in standard laboratory and plant environments. The density of 1.51 g/cm³ indicates a compact molecular structure, while the boiling point of 235.7°C suggests high thermal stability during synthesis reactions. The flash point of 96.4°C requires standard safety precautions during storage and transport. With a refractive index of 1.482, the material demonstrates consistent optical properties batch over batch. These characteristics make it suitable for various reaction conditions including nucleophilic substitutions and cross-coupling reactions.

Industrial Applications

• Serves as a critical building block for synthesizing kinase inhibitors and other therapeutic agents.
• Utilized in the development of advanced agrochemicals requiring fluorinated aromatic structures.
• Employed in material science research for creating specialized polymers and functional materials.
• Acts as a precursor for complex organic molecules in custom synthesis projects.
• Supports process chemistry teams in optimizing reaction pathways for scale-up production.

Quality Assurance and Packaging

We understand that reliability is paramount in chemical supply chains. Each production lot undergoes comprehensive analytical testing using high-performance liquid chromatography (HPLC) and other validated methods to confirm identity and purity. A Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and compliance. The product is packaged in 25 kg drums designed to protect integrity during transit, though custom packaging solutions are available upon request to meet specific logistical needs. Storage recommendations include keeping the material in a cool, ventilated area away from incompatible substances to maintain stability over time. Our global distribution network ensures timely delivery to support your production schedules without compromise.