3-Chloro-4-fluorobenzoic acid
- CAS No.403-16-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity 3-Chloro-4-fluorobenzoic acid (CAS 403-16-7) designed for advanced organic synthesis and pharmaceutical intermediate applications.
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Product Overview
3-Chloro-4-fluorobenzoic acid is a highly valued halogenated aromatic compound that serves as a critical building block in modern organic synthesis. Characterized by its specific substitution pattern on the benzene ring, this chemical entity offers unique reactivity profiles that are essential for the construction of complex molecular architectures. Our facility specializes in the production of this fine chemical with stringent quality controls to ensure consistency across large-scale batches. The presence of both chloro and fluoro substituents provides versatile handles for further functionalization, making it indispensable in medicinal chemistry and agrochemical development.
As a leading global manufacturer, we understand the demands of downstream processors who require reliable supply chains and documented quality. This product is synthesized using advanced catalytic processes that minimize impurities and maximize yield. The resulting material exhibits excellent stability under standard storage conditions, ensuring that its chemical integrity is maintained from our production line to your laboratory or manufacturing floor. We commit to providing comprehensive technical support alongside our product delivery.
Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 3-Chloro-4-fluorobenzoic acid |
| CAS Number | 403-16-7 |
| Molecular Formula | C7H4ClFO2 |
| Molecular Weight | 174.56 g/mol |
| Appearance | White solid |
| Assay (Purity) | ≥99.0% |
| Melting Point | 133-136°C |
| Density | 1.477 g/cm3 |
Industrial Applications
The primary utility of 3-Chloro-4-fluorobenzoic acid lies in its role as a key intermediate for pharmaceutical APIs and agrochemical active ingredients. The fluorine atom introduces metabolic stability to drug candidates, while the chlorine atom offers sites for cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations. Consequently, this compound is frequently utilized in the synthesis of kinase inhibitors, anti-inflammatory agents, and various heterocyclic systems. In the agrochemical sector, it serves as a precursor for herbicides and fungicides where halogenated aromatic cores are required for biological activity.
Beyond pharmaceuticals, this chemical finds application in material science and polymer chemistry. Researchers utilize its reactive carboxylic acid group to form esters, amides, and acid chlorides, facilitating the creation of specialized polymers and liquid crystal materials. Our customers value the high purity levels we maintain, as trace impurities can significantly impact downstream reaction yields and final product quality. We work closely with R&D teams to optimize specifications for specific synthetic routes.
Quality Assurance and Packaging
- Every batch undergoes rigorous analysis using HPLC and NMR to verify structural integrity and purity levels.
- We provide a comprehensive Certificate of Analysis (COA) with each shipment detailing all critical quality attributes.
- Standard packaging consists of 25 kg fiber drums lined with polyethylene bags to ensure moisture protection.
- Custom packaging solutions are available upon request to meet specific logistical or handling requirements.
- Storage recommendations include keeping the material in a cool, ventilated area away from incompatible substances.
Our commitment to quality extends beyond the product itself. We maintain full documentation for regulatory compliance and offer transparent communication regarding lead times and inventory status. Whether you require pilot-scale quantities for research or metric tons for commercial production, our team is equipped to handle your requirements efficiently. Contact our sales department today to discuss your specific needs and request a competitive quote for bulk orders.
