3-Chloro-4-Fluorobenzotrifluoride

Product Overview

3-Chloro-4-Fluorobenzotrifluoride is a specialized fluorinated aromatic compound widely recognized for its stability and reactivity in complex organic synthesis. As a critical building block, this chemical serves as a foundational element in the manufacturing of various pharmaceutical agents and agrochemical products. Our facility ensures that every batch meets rigorous quality standards, providing consistency for downstream processing.

The presence of both chlorine and fluorine substituents on the benzene ring, along with the trifluoromethyl group, imparts unique electronic and steric properties. These characteristics make the compound highly valuable for nucleophilic substitution reactions and cross-coupling processes. We prioritize safety and purity throughout our production lifecycle to support your research and industrial needs.

Technical Specifications

Physical and Chemical Properties

This compound exhibits distinct physical properties that facilitate its handling and integration into synthesis routes. With a boiling point of approximately 136.8 degrees Celsius at 760 mmHg, it can be distilled under standard conditions. The density is recorded at 1.49 g/cm3, indicating a relatively heavy liquid structure typical of polyhalogenated aromatics. The flash point is 42.2 degrees Celsius, necessitating careful storage away from ignition sources.

The refractive index of 1.4355 further confirms the optical purity of the substance. These physical constants are critical for quality control analysts verifying identity and consistency during incoming inspection. Our technical team maintains detailed records of these properties for every production lot.

Industrial Applications

Primarily utilized as an intermediate, 3-Chloro-4-Fluorobenzotrifluoride finds extensive application in the fine chemical industry. It is frequently employed in the synthesis of novel pharmaceutical APIs where fluorinated motifs are required to enhance metabolic stability or bioavailability. Additionally, it serves as a key precursor in the development of advanced agrochemicals, including herbicides and pesticides.

• Pharmaceutical intermediate synthesis
• Agrochemical formulation development
• Fluorinated polymer research
• Custom organic synthesis projects

Storage and Handling

To maintain product integrity, store this chemical in a cool, dry, and well-ventilated area. Keep containers tightly closed when not in use to prevent moisture absorption or contamination. It is essential to keep the substance away from heat, sparks, and open flames due to its flammability characteristics. Always adhere to local safety regulations and consult the safety data sheet before handling.