Intermediates

3-Chloro-4-fluorophenylacetic Acid

  • CAS No.705-79-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Chloro-4-fluorophenylacetic Acid (CAS 705-79-3) designed for advanced organic synthesis. Reliable supply for pharmaceutical and agrochemical intermediate manufacturing.

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Product Technical Details

Product Overview

3-Chloro-4-fluorophenylacetic Acid is a specialized fluorinated organic compound serving as a critical building block in modern chemical synthesis. This halogenated phenylacetic acid derivative combines both chloro and fluoro substituents on the aromatic ring, providing unique reactivity profiles essential for complex molecule construction. Our facility produces this intermediate under strict quality control standards to ensure consistency for downstream applications in medicinal chemistry and agrochemical development.

The strategic placement of halogen atoms enhances the chemical stability and lipophilicity of final products, making this acid a preferred choice for researchers and industrial manufacturers. We supply this material in bulk quantities to support large-scale production needs while maintaining the highest levels of purity and safety compliance.

Chemical Properties And Reactivity

The molecular structure of 3-Chloro-4-fluorophenylacetic Acid features a carboxylic acid group attached to a substituted benzene ring. The presence of electronegative fluorine and chlorine atoms influences the electron density of the aromatic system, facilitating specific coupling reactions such as amide bond formation or esterification. These properties are vital when designing active pharmaceutical ingredients or specialized agrochemical agents.

Physical characteristics include a defined melting point range and specific density, ensuring reliable handling during formulation processes. The compound exhibits low vapor pressure at standard temperatures, contributing to safer storage and transportation conditions within industrial environments. Understanding these physicochemical parameters is crucial for optimizing reaction conditions and maximizing yield in synthetic pathways.

Technical Specifications

ParameterValue
CAS Number705-79-3
Molecular FormulaC8H6ClFO2
Molecular Weight188.583 g/mol
AppearanceWhite crystalline powder
Assay≥98.0%
Melting Point55-58°C
Density1.4±0.1 g/cm3
Boiling Point302.0±27.0 °C at 760 mmHg
Flash Point136.4±23.7 °C

Industrial Applications

This fluorinated intermediate finds extensive use across multiple high-value sectors. In the pharmaceutical industry, it serves as a key precursor for synthesizing kinase inhibitors and other therapeutic agents targeting metabolic disorders. The halogen substituents often improve bioavailability and metabolic stability of the final drug candidates.

  • Pharmaceutical intermediate for novel drug discovery
  • Agrochemical building block for herbicide development
  • Fine chemical synthesis for specialized materials
  • Research and development in organic chemistry

Our global manufacturing network ensures that clients receive materials suitable for rigorous scientific investigation and commercial production. The versatility of this compound allows for diverse functionalization strategies, enabling chemists to explore new chemical spaces efficiently.

Quality Assurance And Storage

Every batch undergoes comprehensive analytical testing including HPLC, NMR, and melting point determination to verify identity and purity. We provide a Certificate of Analysis (COA) with each shipment to document compliance with specified standards. Our quality management system adheres to international guidelines to guarantee product reliability.

For optimal preservation, store this material in a cool, ventilated place away from direct sunlight and moisture. Keep containers tightly closed when not in use to prevent contamination or degradation. Standard packaging includes 25 kg drums, with custom packaging solutions available upon request to meet specific logistical requirements. Proper handling procedures should be followed to ensure safety during transfer and usage.