3-Chloro-4-Iodopyridine
- CAS No.77332-79-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
3-Chloro-4-Iodopyridine is a high-purity halogenated pyridine intermediate designed for advanced organic synthesis and pharmaceutical manufacturing processes.
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Product Overview
3-Chloro-4-Iodopyridine represents a critical building block in the realm of advanced organic synthesis and pharmaceutical development. As a halogenated pyridine derivative, this compound offers unique reactivity profiles due to the presence of both chloro and iodo substituents on the pyridine ring. Our manufacturing process ensures that every batch meets stringent quality standards, making it an ideal choice for research laboratories and industrial-scale production facilities alike.
The compound is characterized by its off-white powder appearance and high thermal stability. The strategic positioning of halogen atoms allows for selective functionalization, enabling chemists to perform various cross-coupling reactions efficiently. This versatility makes it a preferred intermediate for constructing complex molecular architectures found in modern therapeutics and agrochemicals.
Technical Specifications
| Parameter | Value |
|---|---|
| CAS Number | 77332-79-7 |
| Molecular Formula | C5H3ClIN |
| Molecular Weight | 239.44 g/mol |
| Purity (GC) | ≥99.0% |
| Appearance | Off-white powder |
| Melting Point | 105-106°C |
| Boiling Point | 245.0°C |
| Density | 2.052 g/cm³ |
| Refractive Index | 1.642 |
Industrial Applications
Primarily utilized as an intermediate for organic synthesis, 3-Chloro-4-Iodopyridine serves as a foundational element in the creation of diverse chemical entities. Its application spans across multiple sectors including pharmaceuticals, agrochemicals, and material sciences. The high purity level ensures minimal side reactions during synthesis, leading to improved yields and reduced purification costs for downstream processes.
- Pharmaceutical Intermediate: Essential for synthesizing kinase inhibitors and other targeted therapies.
- Cross-Coupling Reactions: Suitable for Suzuki, Heck, and Sonogashira coupling protocols.
- Custom Synthesis: Available for bespoke chemical manufacturing projects requiring specific purity profiles.
- Research and Development: Widely used in academic and industrial labs for novel compound discovery.
Quality Assurance and Storage
We adhere to rigorous quality control protocols to guarantee consistency across all shipments. Each batch is accompanied by a Certificate of Analysis (COA) verifying identity and purity. Proper storage is essential to maintain the integrity of the product. It is recommended to store the material in a cool, ventilated place away from direct sunlight and moisture. Packaging options include 25 kg drums, with flexibility to accommodate specific customer requirements for bulk orders.
Safety handling procedures should strictly follow standard laboratory protocols for halogenated organic compounds. Personal protective equipment including gloves and safety goggles is recommended during handling to prevent irritation. In case of spills, standard chemical containment procedures should be implemented immediately to ensure workplace safety.
Our global distribution network ensures timely delivery to clients worldwide. We understand the critical nature of supply chain continuity in pharmaceutical manufacturing. Therefore, we maintain substantial inventory levels to prevent shortages. Our technical team is available to provide guidance on usage rates, compatibility with other reagents, and optimization of synthesis pathways. Compliance with international regulatory standards is a cornerstone of our operation. We regularly audit our processes to ensure alignment with environmental and safety regulations. This dedication allows our clients to focus on their core research and development activities without worrying about raw material compliance issues.
