Intermediates

3-Chloro-5-fluorobenzoic acid

  • CAS No.25026-64-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity 3-Chloro-5-fluorobenzoic acid (CAS 25026-64-6) designed for advanced organic synthesis. Reliable supply for pharmaceutical and agrochemical intermediate production.

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Product Technical Details

Product Overview

3-Chloro-5-fluorobenzoic acid is a specialized fluorinated aromatic compound widely utilized in the field of fine chemical synthesis. As a key building block, this substance features a unique meta-substitution pattern on the benzene ring, providing distinct electronic and steric properties that are highly valued in modern medicinal chemistry and materials science. Our facility produces this intermediate under strict quality control standards to ensure consistency for downstream applications.

The introduction of both chlorine and fluorine atoms onto the benzoic acid scaffold enhances the metabolic stability and lipophilicity of resulting molecules. This makes the compound an essential precursor for developing advanced pharmaceutical agents, agrochemical protectants, and functional materials. We prioritize industrial purity levels to support complex synthetic routes requiring high reliability.

Technical Specifications

ParameterValue
CAS Number25026-64-6
Molecular FormulaC7H4ClFO2
Molecular Weight174.56 g/mol
AppearanceWhite to off-white solid
Assay (HPLC)≥98.0%
Moisture Content≤0.5%
Melting Point203-205°C
Density1.477 g/cm3

Industrial Applications

This fluorinated benzoic acid derivative serves as a versatile intermediate in organic synthesis. Its primary use cases include the construction of kinase inhibitors and other therapeutic candidates where fluorine substitution is critical for bioavailability. Additionally, it is employed in the synthesis of high-performance polymers and liquid crystal materials due to its thermal stability.

  • Pharmaceutical intermediate synthesis for novel drug discovery.
  • Agrochemical production for crop protection agents.
  • Material science applications requiring halogenated aromatic structures.
  • Custom organic synthesis projects requiring specific meta-substitution.

Quality Assurance and Safety

Every batch undergoes rigorous testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy. We provide a comprehensive Certificate of Analysis (COA) with each shipment to verify purity and identity. Our manufacturing process adheres to international safety standards, ensuring minimal impurities and consistent physical properties.

For storage, the product should be kept in a cool, ventilated area away from incompatible materials. We offer flexible packaging options, including 25 kg drums, customized to meet specific logistical requirements. Our global supply chain ensures timely delivery for research and production scales alike.